Abstract: Objective: To discuss the effects of metronidazole-iodoform gelatin sponge in the prevention of dry socket complications after complicated  tooth extraction. Methods: From January 2005 to January 2010, totally 2 000 teeth in 2 000 patients were extracted, in which1 650 teeth were impacted teeth, and 350 teeth were complicated teeth. They were divided into two groups randomly. Group A (n=1 000), metronidazole-iodoform gelatin sponge was packed in the extraction wound after extraction. Group B (n=1 000), extraction wounds merely filled with blood clots. All patients were followed-up by clinical examination or telephone inquiries at the 3rd, 7th and 14th  day postoperatively. Results: 7 cases of dry socket were found in group A (0.7%), while 80 cases of dry socket were detected in group B (8%), which showed significant difference (P<0.05).  Conclusion: Metronidazole-iodoform gelatin sponge may effectively reduce the incidence of dry socket complications.

Key words: metronidazole-iodoform, gelatin sponge, dry socket, prevention, extraction

摘要： 观察疑难牙拔除术后甲硝唑碘仿明胶海绵预防干槽症的临床疗效。方法： 以2005-01—2010-01到我院口腔门诊拔除下颌阻生齿、下后牙死髓折裂牙患者2 000例，共2 000颗牙为研究对象。其中下颌阻生齿1 650颗，下后牙死髓折裂牙350颗。随机分为2组：研究组（A）1 000例，拔牙后拔牙窝内放入甲硝唑碘仿明胶海绵；对照组（B）1 000例，拔牙后拔牙窝内不放置任何填塞物。术后第3天、第7天专人进行门诊或电话随访，2周后复诊拔牙窝愈合情况。结果： 研究组有7例发生干槽症，发生率为0.7%；对照组有80例发生干槽症，发生率为8%，差异有统计学意义（P＜0.05)。结论： 甲硝唑碘仿明胶海绵用于疑难牙拔除术后预防干槽症的发生，有较好临床效果。

关键词: 甲硝唑碘仿, 明胶海绵, 干槽症, 预防, 拔牙

CLC Number: 

• R782.11