Abstract: Objective：To evaluate the clinical effects of bleomycin, dexamethasone, and sodium morrhuate combined injection on the treatment of oral and facial cavernomas. Methods: 92 infant  patients were divided randomly into two groups. Group A (n=46) was injected with bleomycin, dexamethasone, and sodium morrhuate into the lesion, while group B (n=46) was only injected with bleomycin and dexamethasone. Results: A perfect cure was obtained in all 92 patients. In group A, injection frequency was repeated （3.20±0.13） times and treatment lasted for 20 days.  In group B, the injection frequency was repeated（4.90±0.15） times and lasted for  28 days.  Conclusion： Combination of these three drugs can  shorten the treatment course and reduce the injection frequency. It may be a safe, valid and feasible method and be worthy to widely applying.

Key words: bleomycin, dexamethasone, sodium morrhuate, cavernoma in oral and maxillofacial region

摘要： 目的：探讨平阳霉素、地塞米松、鱼肝油酸钠联合应用进行口腔颌面部静脉畸形瘤体注射的临床疗效。方法：92例颌面部静脉畸形患者随机分为A、B两组，各46例。A组注射平阳霉素、地塞米松、鱼肝油酸钠；B组仅注射平阳霉素、地塞米松。结果：92例患者均治愈。A组平均注射（3.20±0.13）次，疗程20 d。B组平均注射（4.90±0.15）次，疗程28 d。结论：平阳霉素、鱼肝油酸钠、地塞米松联用治疗口腔颌面部血管畸形，可缩短疗程，减少注射次数，安全、有效、易行。

关键词: 平阳霉素, 地塞米松, 鱼肝油酸钠, 颌面部静脉畸形

CLC Number: 

• R732.2