《Journal of Oral and Maxillofacial Surgery》 ›› 2021, Vol. 31 ›› Issue (3): 196-200. doi: 10.3969/j.issn.1005-4979.2021.03.014

• Case Report • Previous Articles    

Nuclear protein of the testis carcinoma of the parotid gland: A case report

HUANG Jinyun1(), REN Guoxin2(), ZHONG Yi3   

  1. 1 School of Stomatology,Weifang Medical University, Weifang 261053, Shandong Province
    2 Department of Oral Maxillofacial Head and Neck Oncology, Shanghai Ninth People′s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011
    3 Department of Traditional Chinese Medicine Oncology, Shanghai Integrated Traditional Chinese and Western Medicine Hospital, Shanghai 200082, China
  • Received:2020-08-29 Revised:2021-02-25 Online:2021-06-28 Published:2021-07-08

腮腺睾丸核蛋白癌1例病例报告

黄金云1(), 任国欣2(), 钟薏3   

  1. 1 潍坊医学院口腔医学院,山东 潍坊 261053
    2 上海交通大学医学院附属第九人民医院口腔颌面头颈肿瘤科,上海 200011
    3 上海市中西医结合医院中医肿瘤科,上海 200082
  • 通讯作者: 任国欣,教授. E-mail: renguoxin@sina.com
  • 作者简介:

    黄金云(1990—),女,山东人,医师,硕士. E-mail:

Abstract:

Nuclear protein of the testis(NUT) carcinoma is a rare and aggressive carcinoma that typically arises from midline structures, frequently from the head and neck area. Under microscope, it has special histopathological manifestations. Immunohistochemistry and fluorescence in situ hybridization(FISH) showed that NUT(+). This article briefly analyzes the clinicopathological characteristics, diagnosis, treatment and differential diagnosis of a case of NUT carcinoma of the parotid gland, and discusses the current diagnosis, treatment and prognosis of NUT carcinoma of the head and neck.

Key words: nuclear protein of the testis carcinoma, head and neck area, parotid gland, diagnosis, prognosis

摘要:

睾丸核蛋白(nuclear protein of the testis, NUT)癌是一种罕见的高度侵袭性恶性肿瘤,通常发生于中线部位,多发生于头颈部。镜下具有独特的组织病理学表现。免疫组织化学及荧光原位杂交(fluorescence in situ hybridization,FISH)结果均显示为NUT(+)。本文对1例腮腺NUT癌的临床病理特征、诊断、治疗及鉴别诊断进行简要分析,探讨目前头颈部NUT癌的诊断、治疗及预后。

关键词: 睾丸核蛋白癌, 头颈部, 腮腺, 诊断, 预后

CLC Number: