Abstract:

Objective: To describe the clinical features, diagnosis, and treatment methods of soft tissue myxoma in oral and maxillofacial region, in order to improve the clinician's understanding of the disease. Methods: The clinical data of 56 patients with soft tissue myxoma in oral and maxillofacial region (including a 31-year-old female reported in this paper) were reviewed and analyzed. Results: A total of 56 patients with soft tissue myxoma in oral and maxillofacial region were included. The male to female ratio was 1.43∶1 and the average age was (37.8 ± 23.9) years. The follow-up was unknown in 9 patients and the median follow-up for the remaining 47 patients was 36(12-60) months. The recurrence rate was 10.6%-14.9%, and the recurrence rates at 2 years and 4 years after surgery were 4.3% and 8.5%, respectively. The recurrence was significantly associated with the number of lesions and treatment methods. Conclusion: Soft tissue myxoma in oral and maxillofacial region is a rare benign tumor that can easily be misdiagnosed and has a high recurrence rate. It is suggested to select an appropriate surgical method according to the location of the tumors and the patient's needs. An ideal outcome is usually achieved by tumor resection with close follow-up for more than 4 years.

Key words: soft tissue myxoma, oral and maxillofacial tumors, recurrence, misdiagnosis, influencing factors

摘要：

目的：探讨口腔颌面部软组织黏液瘤的临床病理特点、诊断及治疗，以提高临床医生对该病的认识。方法：复习文献并分析包括本文报道的1例31岁女性患者在内的56例口腔颌面部软组织黏液瘤的临床资料。结果：纳入分析的56例口腔颌面部软组织黏液瘤患者中，男女比例为1.43∶1，平均年龄为（37.8±23.9）岁。9例随访资料不详，47例患者的中位随访时间为36（12~60）个月，复发率为10.6%~14.9%；术后2年复发率为4.3%，术后4年复发率为8.5%。术后复发的影响因素为病灶的数目和治疗方式。结论：口腔颌面部软组织黏液瘤是一种罕见、易被误诊、可复发的良性肿瘤，建议根据肿瘤部位，结合患者需求选择合适的手术方式。通常情况下，使用单纯肿瘤切除术并保持4年以上的密切随访即可获得理想的疗效。

关键词: 软组织黏液瘤, 口腔颌面部肿瘤, 复发, 误诊, 影响因素

CLC Number: 

• R782