数字化导航辅助右侧下颌骨牙骨质-骨化纤维瘤切除术1例报告及文献复习

doi:10.12439/kqhm.1005-4979.2026.02.011

《口腔颌面外科杂志》 ›› 2026, Vol. 36 ›› Issue (2): 150-154. doi: 10.12439/kqhm.1005-4979.2026.02.011

数字化导航辅助右侧下颌骨牙骨质-骨化纤维瘤切除术1例报告及文献复习

刘玉萍(), 王泰(), 张江宏

银川市口腔医院口腔颌面外科，银川　750000

收稿日期:2024-11-12 接受日期:2025-01-20 出版日期:2026-04-28 上线日期:2026-04-28
通讯作者: 王泰，副主任医师. E-mail: 395760316@qq.com
作者简介:
刘玉萍，主治医师. E-mail: 805167337@qq.com
基金资助:
银川市科技支撑项目(2024SF032)

Digital navigation-assisted resection of cemento-ossifying fibroma in the right mandible: A case report and literature review

LIU Yuping(), WANG Tai(), ZHANG Jianghong

Department of Oral and Maxillofacial Surgery, Yinchuan Stomatology Hospital, Yinchuan 750000, China

Received:2024-11-12 Accepted:2025-01-20 Published:2026-04-28 Online:2026-04-28

摘要/Abstract

摘要：

牙骨质-骨化纤维瘤（cemento-ossifying fibroma，COF）是一种少见的来源于牙源性间充质的颌骨良性肿瘤，好发于下颌骨牙槽突。本文报道1例右侧下颌骨COF患者的临床表现及数字化导航辅助手术的治疗过程，并结合文献复习其诊疗要点，以期为该病的临床诊治提供参考。

关键词: 牙骨质-骨化纤维瘤, 数字化导航, 临床表现, 诊断治疗

Abstract:

Cemento-ossifying fibroma (COF) is a rare benign odontogenic tumor of mesenchymal origin, predominantly occurring in the tooth-bearing areas of the mandible. This article reports a case of COF located in the right mandible, focusing on its clinical manifestations and digital navigation-assisted surgical treatment. A review of the literature is also conducted to discuss the key points of diagnosis and management, aiming to provide reference for the clinical diagnosis and treatment of this disease.

Key words: cemento-ossifying fibroma, digital navigation, clinical manifestations, diagnosis and treatment

中图分类号:

刘玉萍, 王泰, 张江宏. 数字化导航辅助右侧下颌骨牙骨质-骨化纤维瘤切除术1例报告及文献复习[J]. 《口腔颌面外科杂志》, 2026, 36(2): 150-154.

LIU Yuping, WANG Tai, ZHANG Jianghong. Digital navigation-assisted resection of cemento-ossifying fibroma in the right mandible: A case report and literature review[J]. 《Journal of Oral and Maxillofacial Surgery》, 2026, 36(2): 150-154.

https://journal06.magtech.org.cn/Jweb_joms/CN/Y2026/V36/I2/150

图/表 7

图1 术前照片 A.患者正面照；B.口内下颌牙列照。

Figure 1 Preoperative images

图2 术前影像学检查 A.曲面体层片；B. CBCT矢状位提示右下颌骨病变；C. CBCT水平位示颊舌侧膨大；D. CBCT冠状位提示肿物与下牙槽神经位置的关系。红色箭头示病变。

Figure 2 Preoperative imaging examination

图3 术前数字化设计 A.肿物与下牙槽神经位置的关系；B.模拟术后骨缺损范围。

Figure 3 Preoperative digital design

图4 术前及术中位置标定 A—C.根据导航标定手术区域近中上界、近中下界、远中上界；D.通过标定在术区黏膜处定点；E.根据标定区域切开牙龈；F.在牙槽骨上再一次标定手术区域。

Figure 4 Preoperative and intraoperative position calibration

图5 术中照片及离体肿瘤 A.肿物呈实性、淡黄色，包膜完整；B.分块取出肿瘤。

Figure 5 Intraoperative photographs and excised tumor specimen

图6 术后影像学检查 A.术后曲面体层片；B. CT矢状位；C. CT冠状位；D. CT轴位。

Figure 6 Postoperative imaging examination

图7 病理检查图 A.苏木精-伊红（hematoxylin-eosin，HE)染色图可见肿物包膜（×100）；B. HE染色可见纤维组织内大量炎细胞浸润（×200）；C. HE染色可见牙骨质小体（×100）。

Figure 7 Histopathological images

参考文献 20

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