《Journal of Oral and Maxillofacial Surgery》 ›› 2013, Vol. 23 ›› Issue (1): 50-53. doi: 10.3969/j.issn.1005-4979.2013.01.011

• Clinical Report • Previous Articles     Next Articles

Clinicopathology of non-Hodgkin′s Lymphoma in Oral and Maxillofacial Region

HOU Wei-feng, GUO Hai-shan, LI Jun-hong   

  1. 1. Department of Oral and Maxillofacial Surgery, 2. Department of Pathology, Zhengzhou University Luoyang Central Hospital, Luoyang 471009, Henan Province, China
  • Online:2013-02-28 Published:2013-05-08

口腔颌面部非霍奇金淋巴瘤临床病理分析

侯卫锋1,郭海山1,李军红2   

  1. 1. 郑州大学附属洛阳市中心医院口腔颌面外科, 2. 病理科,河南 洛阳 471009
  • 通讯作者: 侯卫锋,主治医师. E-mail: hwf196805@163.com
  • 作者简介:侯卫锋(1968—),男,河南洛阳人,主治医师,学士.

Abstract: Objective: To summarize the clinical pathology and definite diagnosis  of non-Hodgkin′s lymphoma(NHL) in oral and head region. Methods:17 cases with NHL admitted in Luoyang Central Hospital during 2000-02 to 2012-03 were retrospectively reviewed. Results: The patients with NHL have a wide range of age. Males are more than females, the ratio is 2.29∶1. The lesion located in cervical part, submaxillary region, gum, hard or soft palate,  parotid gland, buccal area, and  the base of tongue. The pathological diagnosis were mainly B cell lymphoma. The  definite diagnosis rate was low during first visit. Conclusion: Clinical manifestations of oral-maxillofacial of non-Hodgkin′s lymphomas varied differently, higher requirements are needed in biopsy and pathology examination. Molecular biological detection and close follow-up study is needed in some atypical cases.

Key words: oral and maxillofacial region, lymphoma, clinicopathology

摘要:   目的:探讨与口腔颌面部非霍奇金淋巴瘤确诊相关的临床病理特点。方法:对2000?-02—2012-03郑州大学附属洛阳市中心医院口腔颌面外科收治的17例非霍奇金淋巴瘤,进行回顾性临床病理分析。结果:口腔颌面部非霍奇金淋巴瘤可发生于任何年龄,男女之比为2.4∶1,可发生于颈部及颌下区、牙龈、腭部、腮腺、颊部及舌根部等。病理类型以B细胞淋巴瘤多见。临床及病理首诊确诊率均偏低。结论:口腔颌面部非霍奇金淋巴瘤临床表现多样,确诊依靠病理学诊断,但对取检标本及病理诊断均有较高要求,有些不典型病例需进行分子生物学检测及严密随访。
 

关键词: 口腔颌面部, 淋巴瘤, 临床病理

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