《Journal of Oral and Maxillofacial Surgery》

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Malignant peripheral nerve sheath tumors of the oral and maxillofacial region: report of three cases and review of the literature

Han Shengwei, Han Wei, Sun Guowen, Wang Zhiyong, Hu Qingang   

  1. Department of oral and maxillofacial surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 21008
  • Online:2019-04-01 Published:2019-11-28
  • Supported by:
     

口腔颌面部恶性周围神经鞘膜瘤:3例报告及文献复习

韩生伟,韩伟,孙国文,王志勇,胡勤刚   

  1. 南京大学医学院附属口腔医院口腔颌面外科,江苏 南京 21008
  • 通讯作者: 胡勤刚 主任医师 E-mail:qghu@nju.edu.cn
  • 作者简介:韩生伟(1989-),男,江苏扬州人,博士,主治医师, E-mail:hsw071232003@163.com
  • 基金资助:
    江苏省自然科学基金青年基金(BK20180138);南京市留学人员科技创新项目(2018)

Abstract: Malignant peripheral nerve sheath tumor (MPNST) is a rare malignant tumor of the head and neck region. Related reports are few . This paper reported three cases of MPNST in oral and maxillofacial region since 2015 .By discussing the features of this disease with related literature review, we conclude that recurrence rate after surgery is high and distant metastasis is main cause of death.

Key words: Peripheral nerve sheath tumor, Oral and maxillofacial region, Schwannoma

摘要: 恶性周围神经鞘膜瘤(MPNST)是头颈部极为罕见的一类恶性肿瘤,相关文献报告较少。本文报告了我院2015年以来收治的3例MPNST病例,详细介绍患者治疗及转归情况,并通过结合国内外文献报告探讨该类疾病的特点。该疾病手术后复发率高,而患者死亡的主要原因为远处转移。

关键词: 口腔颌面部, 恶性周围神经鞘膜瘤, 神经鞘瘤

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