Abstract: Objective: To acknowledge the general conditions and characteristics of cleft lip and palate in Gansu province, and to investigate incentive factors associated with the incidence of the disease. Methods:  Retrospective analysis was made on 9 720 cases of cleft lip and palate patients who had received operation from March/2005 to March 2013. Results:  Simple cleft lip was 3 546 cases, combination of cleft lip and palate was 3 888 cases, and simple cleft palate was 2 286 cases. The sex ratio of males and females was 1.62∶1, the ratio of unilateral clefts and bilateral ones was 4.44∶1, the ratio of the left lip and the right was 2.07∶1, the ratio between rural areas and the urban was 5.04∶1. Patients from Longnan city accounted for 40.78 percentage of total patients. Level of education of patients' mother under junior high  accounted for 85.05%. Conclusion: Longnan region dominant the cleft lip and cleft palate cases in Gansu province. The geographical environment, and genetic factors may be the risk factors of congenital cleft lip and palate. No relationship between mother's education and the occurrence of cleft lip and palate was found.

Key words: cleft lip, cleft palate, clinical data analysis

摘要： 目的： 了解近年来甘肃省先天性唇腭裂的发病情况，探讨与其发病有关的影响因素，为该病的预防与治疗提供依据。方法： 收集并统计分析2005-03—2013-03间，在甘肃省人民医院口腔颌面外科进行唇腭裂手术的9 720例患者的临床资料。结果： 唇裂3 546例 、唇裂伴腭裂3 888例、腭裂2 286例 ；男女比为 1.62∶1；单侧与双侧唇腭裂比为4.44∶1 ；左侧与右侧比为2.07∶1；农村与城市的患儿比为5.04:1；陇南市患者占总人数的40.78%；母亲文化水平为初中以下的占总人数的85.05%。结论： 陇南地区唇腭裂患者占多数;唇裂合并腭裂居多；左侧多于右侧；男性多于女性；农村多于城市。遗传因素和地理环境因素可能是甘肃省内先天性唇腭裂的危险因素。而母亲文化程度的高低与唇腭裂的发生无相关性。

关键词: 唇裂, 腭裂, 临床资料分析

CLC Number: 

• R782.2