| [1] Llewellyn CD, Linklater K, Bell J, et al. Squamous cell carcinoma of the oral cavity in patients aged 45 years and under: a descriptive analysis of 116 cases diagnosed in the South East of England from 1990 to 1997[J]. Oral Oncology, 2003, 39(2):106-114.
[2] Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer[J]. New England J Med, 2010, 363(1): 24-35.
[3] Mizushima N. Autophagy: process and function[J]. Genes Development, 2007, 21(22):2861-2873.
[4] Hotchkiss RS, Strasser A, Mcdunn JE, et al. Cell death[J]. New England J Med, 2009, 361(16):1570-1583.
[5] Alers S, L?觟ffler AS, Wesselborg S, et al. Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks[J]. Mol Cell Biol, 2012, 32(1):2-11.
[6] Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation[J]. Curr Opin Cell Biol, 2010, 22(2):124-131.
[7] St?覿mpfli MR, Anderson GP. How cigarette smoke skews immune responses to promote infection, lung disease and cancer[J]. Nat Rev Immunol, 2009, 9(5):377-384.
[8] Mishra NC, Rirsimaah J, Langley RJ, et al. Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens[J]. J Immunol, 2008, 180(11):7655-7663.
[9] Hamid A, Kaur J. Long-term alcohol ingestion alters the folate-binding kinetics in intestinal brush border membrane in experimental alcoholism[J]. Alcohol, 2007, 41(6):441-446.
[10] Ratovitski EA. ΔNp63α/IRF6 interplay activates NOS2 transcription and induces autophagy upon tobacco exposure[J]. Arch Biochem Biophys, 2011, 506(2):208-215.
[11] Saburo I, Jun A, Yusuke K, et al. PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis[J]. Autophagy, 2015, 11(3):547-559.
[12] Furlong HC, St?mpfli MR, Gannon AM, et al. Cigarette Smoke Exposure Triggers the Autophagic Cascade via Activation of the AMPK Pathway in Mice[J]. Biol Reprod, 2015, 93(4):93.
[13] Wang S, Zhang C, Zhang M, et al. Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo[J]. Nature Medicine, 2012, 18(6):902-910.
[14] Lu HH, Kao SY, Liu TY, et al. Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells[J]. Autophagy, 2010, 6(6):725-737.
[15] Hwang JW, Chung S, Sundar IK, et al. Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD[J]. Arch Biochem Biophys, 2010, 500(2):203-209.
[16] Lin MH, Hsieh WF, Chiang WF, et al. Corrigendum to "Autophagy induction by the 30-100kDa fraction of areca nut in both normal and malignant cells through reactive oxygen species"[J]. Oral Oncology, 2010, 46(11):822-828.
[17] Betiol JC, Laura S, Olival CHOD, et al. Prevalence of human papillomavirus types and variants and p16INK4aexpression in head and neck squamous cells carcinomas in S?覿o Paulo, Brazil[J]. Infect Agent Cancer, 2016, 11(1):1-7.
[18] Gillison ML, Koch WM, Capone RB, et al. Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers[J]. J National Cancer Inst, 2000, 92(9):709-720.
[19] Mclaughlindrubin ME, Münger K. The human papillomavirus E7 oncoprotein[J]. Virology, 2009, 384(2):335-344.
[20] Chen SF, Yu FS, Chang YC, et al. Role of human papillomavirus infection in carcinogenesis of oral squamous cell carcinoma with evidences of prognostic association[J]. J Oral Pathol Med, 2012, 41(1):9-15.
[21] Griffin L M, Cicchini L, Pyeon D. Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes[J]. Virology, 2013, 437(1):12-9.
[22] Surviladze Z, Sterk RT, Deharo SA, et al. Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy[J]. J Virol, 2013, 87(5):2508-2517.
[23] Zhou X, Münger K. Expression of the Human Papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivation[J]. Virology, 2009, 385(1):192-197.
[24] Leemans CR, Braakhuis BJ, Brakenhoff RH. The molecular biology of head and neck cancer[J]. Nature Reviews Cancer, 2011, 11(1):9-22.
[25] Network CGA. Comprehensive genomic characterization of head and neck squamous cell carcinomas[J]. Nature, 2015, 517(7536):576-582.
[26] Macha MA, Matta A, Chauhan SS, et al. Guggulsterone Targets Smokeless Tobacco Induced PI3K/Akt Pathway in Head and Neck Cancer Cells[J]. Plos One, 2011, 6(2):e14728.
[27] Leemans CR, Braakhuis BJ, Brakenhoff RH. The molecular biology of head and neck cancer[J]. Nature Reviews Cancer, 2011, 11(1):9-22.
[28] Maiuri MC, Galluzzi L, Morselli E, et al. Autophagy regulation by p53[J]. Current Opinion in Cell Biology, 2010, 22(2):181-185.
[29] Poeta ML, Manola J, Goldwasser MA, et al. TP53 Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck[J]. New Engl J Med, 2007, 357(25):2552-2561.
[30] Zhao M, Mydlarz WK, Zhou S, et al. Head and neck cancer cell lines are resistant to mitochondrial-depolarization-induced apoptosis[J]. Orl J Otorhinolaryngol Relat Spec, 2008, 70(4):257-263.
[31] Ang KK, Berkey BA, Tu X, et al. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma[J]. Cancer Research, 2002, 62(24):7350-7356.
[32] Wei Y, Zou Z, Becker N, et al. EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance[J]. Cell, 2013, 154(6):1269-1284.
[33] Carracedo A, Pandolfi PP. The PTEN-PI3K pathway: of feedbacks and cross-talks[J]. Oncogene, 2008, 27(41):5527-5541.
[34] 白宇, 全海英, 张桐菲,等. 顺铂诱导的自噬在口腔鳞癌Tca83细胞中的作用[J]. 口腔医学研究, 2012, 28(6):566-569.
[35] Altmeyer A, Jung AC, Ignat M, et al. Pharmacological enhancement of autophagy induced in a hepatocellular carcinoma cell line by high-LET radiation[J]. Anticancer Research, 2010, 30(2):303-310.
[36] Jerhammar F, Ceder R, Garvin S, et al. Fibronectin 1 is a potential biomarker for radioresistance in head and neck squamous cell carcinoma[J]. Cancer Biology Therapy, 2010, 10(12):1244-1251.
[37] Lin TY, Chang TC, Wang HM, et al. Proteomics of the Radioresistant Phenotype in Head-and-Neck Cancer: Gp96 as a Novel Prediction Marker and Sensitizing Target for Radiotherapy[J]. Int J Radiat Oncology Biol Physics, 2010, 78(1):246-256.
[38] Zhou ZR, Zhu XD, Zhao W, et al. Poly(ADP-ribose) polymerase-1 regulates the mechanism of irradiation-induced CNE-2 human nasopharyngeal carcinoma cell autophagy and inhibition of autophagy contributes to the radiation sensitization of CNE-2 cells[J]. Oncology Reports, 2013, 29(6):2498-2506.
[39] Nam HY, Han MW, Chang HW, et al. Radioresistant Cancer Cells Can Be Conditioned to Enter Senescence bymTOR Inhibition[J]. Cancer Research, 2013, 73(14):4267-4277.
[40] Wang Y, Yin W, Zhu X. Blocked autophagy enhances radiosensitivity of nasopharyngeal carcinoma cell line CNE-2 in vitro[J]. Acta Otolaryngol, 2014, 134(1):105-110.
[41] Mo N, Lu YK, Xie WM, et al. Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing Rad51 expression[J]. Oncol Rep, 2014, 32(5):1905-1912.
[42] Song Y, Li W, Peng X, et al. Inhibition of autophagy results in a reversal of taxol resistance in nasopharyngeal carcinoma by enhancing taxol-induced caspase-dependent apoptosis[J]. Am J Transl Res, 2017, 9(4):1934-1942.
[43] Yen CY, Chiang WF, Liu SY, et al. Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity[J]. Journal of Oral Pathol Med, 2014, 43(2):91-96.
[44] Zhao X, Sun R, Yang X, et al. Chloroquine-Enhanced Efficacy of Cisplatin in the Treatment of Hypopharyngeal Carcinoma in Xenograft Mice[J]. Plos One, 2015, 10(4):e0126147.
[45] Mericbernstam F, Gonzalezangulo AM. Targeting the mTOR Signaling Network for Cancer Therapy[J]. J Clin Oncol, 2009, 27(13):2278-2287.
[46] Qian W, Liu J, Jin J, et al. Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1[J]. Leukemia Research, 2007, 31(3):329-339.
[47] Wang YF, Zhang W, He KF, et al. Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma[J]. Apoptosis, 2014, 19(4):748-758.
[48] Hegymegibarakonyi B, Eros D, Szántaikis C, et al. Tyrosine kinase inhibitors-small molecular weight compounds inhibiting EGFR[J]. Curr Opin Mol Ther, 2009, 11(3):308-321. |