<div>
	二氧化碳点阵激光早期治疗一期唇裂术后瘢痕的临床疗效
</div>

doi:10.12439/kqhm.1005-4979.2024.05.001

摘要/Abstract

摘要：

目的：评估二氧化碳点阵激光早期治疗一期唇裂术后瘢痕的临床疗效。方法：选取本中心接受一期唇裂整复术的患儿 24 例（激光组），术后 3 个月内采用二氧化碳点阵激光治疗；对照组（24 例）为曾接受一期唇裂整复术，术后未接受激光治疗的患儿。对 2 组一期患儿激光治疗后 1 年的瘢痕情况进行主观评价（对比患儿治疗前后照片）和客观评价 [ 使用温哥华瘢痕量表（Vancouver scar scale，VSS）评分法 ]。结果：激光组完成整个疗程 4 次治疗后 1 年，主观评价总有效率达到 91.7%，2 组差异有统计学意义（P<0.05）。客观评价结果显示，2 组差异有统计学意义（P<0.05）。结论：应用二氧化碳点阵激光早期治疗一期唇裂术后瘢痕的方法疗效确切，值得临床推广应用。

关键词:

二氧化碳点阵激光, 一期唇裂, 瘢痕, 早期治疗

Abstract:

[Abstract] Objective: To evaluate the clinical effect of carbon dioxide fractional laser in early treatment of postoperative scar of primary cleft lip. Methods: A total of 24 children who had undergone primary cleft lip repair in the treatment group were treated with carbon dioxide fractional laser within three months after operation, and 24 children who had undergone primary cleft lip repair in the control group were not treated with laser after operation. Based on the subjective assessment by comparing photographs before and after the treatment and the objective assessment using Vancouver scar scale (VSS) scoring method, the scar conditions of the two groups were compared one year after laser therapy. Results: The total effective rate of the treatment group was 91.7% after the completion of the whole course of 4 treatments after 1 year, and the difference between the two groups was statistically significant (P<0.05). The objective assessment results showed that the difference between the two groups was statistically significant (P<0.05). Conclusion: Carbon dioxide fractional laser is effective in the early treatment of postoperative scar of primary cleft lip, which is worthy of clinical application.

Key words:

carbon dioxide fractional laser, primary cleft lip, scar, early treatment

中图分类号:

R782

吴敏, 尹恒, 黄汉尧, 石冰, 李承浩.

二氧化碳点阵激光早期治疗一期唇裂术后瘢痕的临床疗效

[J]. 《口腔颌面外科杂志》, 2024, 34(5): 331-335.

WU Min, YIN Heng, HUANG Hanyao, SHI Bing, LI Chenghao.

Clinical efficacy of carbon dioxide fractional laser in the early treatment of scars after primary cleft lip surgery

[J]. 《Journal of Oral and Maxillofacial Surgery》, 2024, 34(5): 331-335.

https://journal06.magtech.org.cn/Jweb_joms/CN/Y2024/V34/I5/331

参考文献

[1] Kerwin LY, El Tal AK, Stiff MA, et al. Scar prevention and remodeling: A review of the medical, surgical, topical and light treatment approaches[J]. Int J Dermatol, 2014, 53(8): 922-936.

[2] Mossaad A, Kotb A, Abdelrahaman M, et al. Post-surgical repair of cleft scar using fractional CO2 laser[J]. Open Access Maced J Med Sci, 2018, 6(7): 1231-1234.

[3] Cohen JL, Geronemus R. Safety and efficacy evaluation of pulsed dye laser treatment, CO2 ablative fractional resurfacing, and combined treatment for surgical scar clearance[J]. J Drugs Dermatol, 2016, 15(11): 1315-1319.

[4] Kim DH, Ryu HJ, Choi JE, et al. A comparison of the scar prevention effect between carbon dioxide fractional laser and pulsed dye laser in surgical scars[J]. Dermatol Surg, 2014, 40(9): 973-978.

[5] 李媛媛, 吴敏, 刘明曦, 等. CO2 点阵激光早期控制唇裂二期整复术后瘢痕的疗效观察 [J]. 华西口腔医学杂志, 2020, 38(6): 657-661.

[6] Seo YA, Kim YA. Factors affecting acceptance of cosmetic surgery in adults in their 20s-30s[J]. Aesthetic Plast Surg, 2020, 44(5): 1881-1888.

[7] 周露琪, 胡丽, 仇雅璟, 等. 面部手术切口瘢痕的早期干预 [J]. 组织工程与重建外科杂志, 2021, 17(4): 358-362.

[8] Tan JL, Zhou JY, Huang L, et al. Hypertrophic scar improvement by early intervention with ablative fractional carbon dioxide laser treatment[J]. Lasers Surg Med, 2021, 53(4): 450-457.

[9] Tian LY, Li YL, Wu Y, et al. Meta-analysis of efficacy of pressure therapy in treating patients with hypertrophic scars[J]. Chin J Burns, 2019, 35(9): 668-675.

[10] 施晓晓, 汤諹. 瘢痕评估量表的文献复习 [J]. 中国皮肤性病学杂志, 2014, 28(5): 527-529.

[11] 中国整形美容协会瘢痕医学分会. 瘢痕早期治疗全国专家共识 (2020 版 )[J]. 中华烧伤杂志, 2021, 37(2): 113-125.

[12] Ibrahim SM, Saudi WM, Abozeid MF, et al. Early fractional carbon dioxide laser intervention for postsurgical scars in skin of color[J]. Clin Cosmet Investig Dermatol, 2019, 12: 29-34.

[13] 张晨颖, 张高飞, 娄涵潇, 等. 剥脱性二氧化碳点阵激光在烧烫伤瘢痕中的临床应用研究进展 [J]. 实用医学杂志, 2021, 37(19): 2554-2558.

[14] Yang ZZ, Lv Y, Yue F, et al. Early intervention of fractional carbon dioxide laser on fresh traumatic scar[J]. Lasers Med Sci, 2019, 34(7): 1317-1324.

[15] Clementoni MT, Pedrelli V, Zaccaria G, et al. New developments for fractional CO2 resurfacing for skin rejuvenation and scar reduction[J]. Facial Plast Surg Clin North Am, 2020, 28(1): 17-28.

[16] Zhang C, Yin K, Shen YM. Efficacy of fractional carbon dioxide laser therapy for burn scars: A meta-analysis[J]. J Dermatolog Treat, 2021, 32(7): 845-850.

[17] 王琼, 谭军. 点阵激光治疗瘢痕后创面愈合过程中真皮-表皮连接区组织学变化及研究进展 [J]. 中国烧伤创疡杂志, 2014, 26(1): 55-59.

[18] 谭军. 激光治疗瘢痕的现状与展望 [J]. 中国美容医学, 2017, 26(2): 1-4.

[19] DeBruler DM, Blackstone BN, Baumann ME, et al. Inflammatory responses, matrix remodeling, and re-epithelialization after fractional CO2 laser treatment of scars[J]. Lasers Surg Med, 2017, 49(7): 675-685.

[20] 陈永平, 王金河. 点阵超脉冲 CO2 激光联合表皮生长因子凝胶治疗痤疮瘢痕的临床观察 [J]. 应用激光, 2018, 38(6): 1063-1067.

[21] 杨进平, 贾冬梅. 超脉冲二氧化碳点阵激光联合重组牛碱性成纤维细胞生长因子外用溶液治疗面部凹陷性痤疮疤痕疗效观察 [J]. 医学美学美容, 2020, 29(7): 10-11.

[22] Diegelmann RF, Evans MC. Wound healing: An overview of acute, fibrotic and delayed healing[J]. Front Biosci, 2004, 9: 283-289.

[23] Paul J Carniol, Amish Talwar, Eric T Carniol. Laser treatment of facial scars[J]. Facial Plast Surg, 2010, 26(6): 519-521.

[24] Du FY, Yu YS, Zhou ZQ, et al. Early treatment using fractional CO2 laser before skin suture during scar revision surgery in Asians[J]. J Cosmet Laser Ther, 2018, 20(2): 102-105.

[25] Capon A, Souil E, Gauthier B, et al. Laser assisted skin closure (LASC) by using a 815 nm diode-laser system accelerates and improves wound healing[J]. Lasers Surg Med, 2001, 28(2): 168-175.

选择文件类型/文献管理软件名称

选择包含的内容

二氧化碳点阵激光早期治疗一期唇裂术后瘢痕的临床疗效

Clinical efficacy of carbon dioxide fractional laser in the early treatment of scars after primary cleft lip surgery

PDF

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 2

编辑推荐

Metrics

本文评价

[1]	王浩然, 王映, 李志萍, 庄乾伟, 孟箭, 葛良玉. 两种术式前臂皮瓣术后前臂供区恢复的比较[J]. 《口腔颌面外科杂志》, 2021, 31(4): 232-236.
[2]	柳宏志，邹高峰，王天祥，李超. 浓缩生长因子促进犬软组织损伤修复的实验研究[J]. 《口腔颌面外科杂志》, 2013, 23(1): 28-31.

模态框（Modal）标题

选择文件类型/文献管理软件名称

选择包含的内容

二氧化碳点阵激光早期治疗一期唇裂术后瘢痕的临床疗效

Clinical efficacy of carbon dioxide fractional laser in the early treatment of scars after primary cleft lip surgery

PDF

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 2

编辑推荐

Metrics

本文评价