《口腔颌面外科杂志》 ›› 2025, Vol. 35 ›› Issue (4): 324-330. doi: 10.12439/kqhm.1005-4979.2025.04.013

• 病例报告 • 上一篇    

成人下颌骨朗格汉斯细胞组织细胞增生症治疗1例报告及文献复习

莫玮彦(), 刘士维, 陈巨峰, 李金()   

  1. 佛山市第一人民医院口腔医学中心,佛山 528000
  • 收稿日期:2024-04-11 接受日期:2024-08-26 出版日期:2025-08-28 上线日期:2025-08-28
  • 通讯作者: 李金,主任医师. E-mail: lijinkq99655@163.com
  • 作者简介:
    莫玮彦,住院医师. E-mail:

Mandibular Langerhans cell histiocytosis in an adult: A case report and literature review

MO Weiyan(), LIU Shiwei, CHEN Jufeng, LI Jin()   

  1. The Stomatology Medical Center, the First People's Hospital of Foshan, Foshan 528000, China
  • Received:2024-04-11 Accepted:2024-08-26 Published:2025-08-28 Online:2025-08-28

摘要:

朗格汉斯细胞组织细胞增生症(Langerhans cell histiocytosis,LCH)是一种病因不明、可累及多器官/系统的罕见病。本文报道1例接受手术治疗并行血管化腓骨肌皮瓣修复术,术后出现尿崩症(diabetes insipidus,DI)的成人LCH病例,并结合相关文献,围绕LCH的发病机制、临床特征、诊断标准和治疗策略等进行系统讨论。

Abstract:

Langerhans cell histiocytosis (LCH) is a rare disease with an unknown etiology. It can involve multiple organs/systems. This is a clinical report presenting surgical treatment and reconstruction with a vascularized fibular musculocutaneous flap in an adult patient with mandibular LCH. The patient was diagnosed with diabetes insipidus (DI) after surgery. Based on relevant literature, the pathogenesis, clinical characteristics, diagnosis and treatment strategies of LCH are systematically discussed in this article.

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