《Journal of Oral and Maxillofacial Surgery》 ›› 2013, Vol. 23 ›› Issue (2): 98-100. doi: 10.3969/j.issn.1005-4979.2013.02.005

• Clinical Study • Previous Articles     Next Articles

Brain Activity and Facial Tactile in Trigeminal Maxillary Division: An Functional MRI Study

LI Jia1,2, LIU Hong-chen2, LI Ke3, JIN Zhen3, ZHU Xia1   

  1. 1.Laboratory of Oral Biomedical Science and Translational Medicine, School of Stomatology, Tongji University, Shanghai, 200072;2.Department of Stomatology, The PLA General Hospital, Beijing 100853;3. Department of Radiology, PLA 306 Hospital, Beijing 100101, China
  • Online:2013-04-28 Published:2013-07-03
  • Supported by:

    国家自然科学基金资助项目(30772450)

触觉刺激三叉神经上颌支面部支配区的功能性MRI研究

李家1,2, 刘洪臣2, 李科3, 金真3, 朱霞1   

  1. 1.同济大学口腔医学院生物医学及转化实验室,上海 202072;
    2.解放军总医院口腔医学院研究所,北京 100083;3.解放军306医院放射科,北京 100101
  • 通讯作者: 刘洪臣,教授,主任医师. E-mail:cjgd@301dent.com
  • 作者简介:李家(1974—),男,河北人, 主治医师, 博士 E-mail:lidentist74@sina.com

Abstract: Objective: To evaluate the brain cortical response to facial tactile in maxillary trigeminal division. Methods:8 healthy volunteers participated in the study. Cotton-tipped swab stimuli was applied to right side of face in maxillary trigeminal division, and block designed BOLD functional MRI scan covering the whole brain was carried out. Results:Increased BOLD signals during tactile stimulation were found in left SI (BA3), insula/SII, Brodman's area 22,45, and right Brodman's area 40,9,38,41. Conclusion:Tactile stimuli activated contralateral primary, secondary somatosensory cortex, superior temporal gyrus, ipsilateral postcentral gyrus , inferior temporal gyrus, transverse temporal gyrus, bilateral prefrontal cortex .
 

Key words: maxillofacial region; tactile; cortex, functional MRI (fMRI)

摘要:  目的: 观察触觉刺激三叉神经上颌支(简称V2)面部支配区引起的大脑中枢反应区。 方法: 选取8名健康志愿者,用棉签刺激右侧面部三叉神经上颌支的支配区,采用触觉刺激减静息的组块设计方法,采集全脑血氧水平依赖对比的功能性MRI扫描数据。结果: 脑激活区为左侧初级躯体感觉皮质(BA3)、岛叶/SII、BA22、BA45,右侧BA40、BA9、BA38、BA41。结论: 对侧初级躯体感觉皮质、岛叶/SII和颞上回,同侧中央后回、颞下回和颞横回及双侧前额皮质是面部V2区触觉刺激激活的脑部功能区。 

关键词:  , 颌面部;触觉;大脑皮质;功能性磁共振成像(fMRI)

CLC Number: