Modern Trends in Multiple Growth Factors Delivery System for Tissue Engineering

doi:10.3969/j.issn.1005-4979.2016.02.013

Abstract

Abstract: Growth factors are a group of activated proteins synthesized and excreted from cells, which play a critical role in wound healing, tissue repair and tissue regeneration. Natural tissue repair and regeneration processes are regulated by multiple growth factors, thus mimic the natural healing processes, controlled release multiple growth factors is a promising application in tissue engineering.

Key words: growth factor, carrier, release pattern, tissue engineering

摘要： 生长因子是细胞合成和分泌的一类活性蛋白质，在促进组织再生、修复及创伤愈合等方面发挥重要作用。生理性的组织修复与再生过程是在多种生长因子共同调节下完成的，因此模拟生理性组织修复过程，可控性释放多种生长因子在组织工程领域具有广阔的应用前景。

关键词: , 生长因子, , , 载体, , , 释放模式, , , 组织工程

CLC Number:

R782.2

LIU Ning, WANG Zuo-lin. Modern Trends in Multiple Growth Factors Delivery System for Tissue Engineering[J]. 《Journal of Oral and Maxillofacial Surgery》, 2016, 26(2): 135-139.

刘宁，王佐林. 多因子释放系统在组织工程领域的应用[J]. 《口腔颌面外科杂志》, 2016, 26(2): 135-139.

/ / Recommend / Download Citations

URL: https://journal06.magtech.org.cn/Jweb_joms/EN/10.3969/j.issn.1005-4979.2016.02.013

https://journal06.magtech.org.cn/Jweb_joms/EN/Y2016/V26/I2/135

References

[1] Fernandez-Yague MA, Abbah SA, McNamara L, et al. Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies[J]. Adv Drug Deliv Rev, 2015, 84:1-29.

[2] Castro NJ, O'Brien J, Zhang LG. Integrating biologically inspired nanomaterials and table-top stereolithography for 3Dprinted biomimeticosteochondralscaffolds[J]. Nanoscale, 2015, 7(33):14010-14022.

[3] Minardi S, Pandolfi L, Taraballi F, et al. PLGA-Mesoporous Silicon Microspheres for the in Vivo Controlled Temporospatial Delivery of Proteins[J]. ACS Appl Mater Interfaces, 2015, 7(30):16364-16373

[4] Yun YR, Jang JH, Jeon E, et al. Administration of growth factors for bone regeneration[J]. Regen Med, 2012, 7(3):369-385.

[5] Mehta M, Schmidt-Bleek K, Duda GN, et al. Biomaterial delivery of morphogens to mimic the natural healing cascade in bone[J]. Adv Drug Deliv Rev, 2012, 64(12):1257-1276.

[6] 王姹，徐燕. 生长因子在牙周组织再生中的有效释放方式[J]. 国际口腔医学杂志, 2012(2):265-268.

[7] Izadifar M, Haddadi A, Chen X, et al. Rate-programming of nano-particulate delivery systems for smart bioactive scaffolds in tissue engineering[J]. Nanotechnology, 2015, 26(1):012001.

[8] Chaudhary LR, Hofmeister AM, Hruska KA. Differential growth factor control of bone formation osteoprogenitor differentiation[J]. Bone, 2004, 34(3):402-411.

[9] Langdahl BL, Kassem M, Moller MK, et al. The effects of IGF-I and IGF-II on proliferation and differentiation of human osteoblasts and interactions with growth hormone[J]. Eur J Clin Invest, 1998,28(3):176-183.

[10] Samorezov JE, Alsberg E. Spatial regulation of controlled bioactive factor delivery for bone tissue engineering[J]. Adv Drug Deliv Rev, 2015,84:45-67.

[11] Lee K, Silva EA, Mooney DJ. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments[J]. J R Soc Interface, 2011, 8(55):153-170.

[12] Suarez-Gonzalez D, Lee JS, Diggs A, et al. Controlled multiple growth factor delivery from bone tissue engineering scaffolds via designed affinity[J]. Tissue Eng Part A, 2014, 20(15-16):2077-2087.

[13] Vasita R, Katti DS. Growth factor-delivery systems for tissue engineering: a materials perspective[J]. Expert Rev Med Devices, 2006, 3(1):29-47.

[14] Bhargava MM, Hidaka C, Hannafin JA, et al. Effects of hepatocyte growth factor and platelet-derived growth factor on the repair of meniscal defects in vitro[J]. In Vitro Cell Dev Biol Anim, 2005, 41(8-9):305-310.

[15] Schwartz-Arad D, Ofec R, Eliyahu G, et al. Long term follow-up of dental implants placed in autologous onlay bone graft[J]. Clin Implant Dent Relat Res, 2014, doi:10.111/cid.12288.

[16] Anitua E, Tejero R, Zalduendo MM, et al. Plasma rich in growth factors promotes bone tissue regeneration by stimulating proliferation, migration, and autocrine secretion in primary human osteoblasts[J]. J Periodontol, 2013, 84(8):1180-1190.

[17] Yu X, Khalil A, Dang PN, et al. Multilayered inorganic microparticles for tunable dual growth factor delivery[J]. Adv Funct Mater, 2014, 24(20):3082-3093.

[18] Raiche AT, Puleo DA. Cell responses to BMP-2 and IGF-I released with different time-dependent profiles[J]. J Biomed Mater Res A, 2004, 69(2):342-350.

[19] Teng W, Wang Q, Chen Y, et al. Controllably local gene delivery mediated by polyelectrolyte multilayer films assembled from gene-loaded nanopolymersomes and hyaluronic acid[J]. Int J Nanomedicine, 2014, 9:5013-5024.

[20] Qiu T, Chen Y, Song J, et al. Preparation of cross-linked, multilayer-coated fluorescent microspheres with functional groups on the surface for bioconjugation[J]. ACS Appl Mater Interfaces, 2015,7(15):8260-8267.

[21] Richardson TP, Peters MC, Ennett AB, et al. Polymeric system for dual growth factor delivery[J]. Nat Biotechnol, 2001, 19(11):1029-1034.

[22] Burdick JA, Ward M, Liang E, et al. Stimulation of neurite outgrowth by neurotrophins delivered from degradable hydrogels[J]. Biomaterials, 2006, 27(3):452-459.

[23] Charles LF, Woodman JL, Ueno D, et al. Effects of low dose FGF-2 and BMP-2 on healing of calvarial defects in old mice[J]. Exp Gerontol, 2015, 64:62-69.

[24] Censi R, Dubbini A, Matricardi P. Bioactive hydrogel scaffolds - advances in cartilage regeneration through controlled drug delivery[J]. Curr Pharm Des, 2015, 21(12):1545-1555.25] Lu Y, Sun W, Gu Z. Stimuli-responsive nanomaterials for therapeutic protein delivery[J]. J Control Release, 2014, 194:1-19.

[26] 唐功文，赵蕴慧，袁晓燕. 微球-三维支架复合体系控制释放生长因子的研究进展[J]. 高分子通报, 2012(12):8-15.

[27] Kim K, Lam J, Lu S, et al. Osteochondral tissue regeneration using a bilayered composite hydrogel with modulating dual growth factor release kinetics in a rabbit model[J]. J Control Release, 2013, 168(2):166-178.

[28] Chen FM, Chen R, Wang XJ, et al. In vitro cellular responses to scaffolds containing two microencapulated growth factors[J]. Biomaterials, 2009, 30(28):5215-5224.

[29] Lv J, Xiu P, Tan J, et al. Enhanced angiogenesis and osteogenesis in critical bone defects by the controlled release of BMP-2 and VEGF: implantation of electron beam melting-fabricated porous Ti6Al4V scaffolds incorporating growth factor-doped fibrin glue[J]. Biomed Mater, 2015, 10(3):035013.

[30] Yu Y, Chen J, Chen R, et al. Enhancement of VEGF-Mediated Angiogenesis by 2-N,6-O-Sulfated Chitosan-Coated Hierarchical PLGA Scaffolds[J]. ACS Appl Mater Interfaces, 2015,7(18):9982-9990.

[31] Mirdailami O, Soleimani-, Dinarvand R, et al. Controlled release of rhEGF and rhbFGF from electrospun scaffolds for skin regeneration[J]. J Biomed Mater Res A, 2015, 103(10):3374-3385.

[32] Bera T, Freeman EJ, Mcdonough JA, et al. Liquid Crystal Elastomer Microspheres as Three-Dimensional Cell Scaffolds Supporting the Attachment and Proliferation of Myoblasts[J]. ACS Appl Mater Interfaces, 2015,7(26):14528-14535.

[33] Lam J, Lu S, Kasper FK, et al. Strategies for controlled delivery of biologics for cartilage repair[J]. Adv Drug Deliv Rev, 2015, 84:123-134.

[34] Borcard F, Kong P, Journot C, et al. Surface modification of biomaterials for conjugation with human fetal osteoblasts[J]. Chimia (Aarau), 2013, 67(4):213-217.

[35] Morachis JM, Mahmoud EA, Almutairi A. Physical and chemical strategies for therapeutic delivery by using polymeric nanoparticles[J]. Pharmacol Rev, 2012, 64(3):505-519.

Please choose a citation manager

Content to export