Recent Advance on the Application of Pearl Powder，rhBMP-2 and their Complex in Bone Engineering

doi:10.3969/j.issn.1005-4979.2018.03.011

Abstract

Abstract: Pearl powder has been one of the hotspots in the research of bioengineering materials to explore the ideal bone repair materials suitable for clinical application. Recombinant human bone morphogenetic protein 2(rhBMP-2) is a known growth factor to promote fracture healing, and is widely used in bone tissue engineering. This article aims to summarize the potentials as well as the problems of the pearl powder , rhBMP-2 and their complex in bone engineering.

Key words: pearl powder, rhBMP-2, tissue engineering, bone substitute

摘要： 探寻适用于临床的理想骨修复材料一直是生物工程材料研究的热点之一。珍珠粉作为天然的有机材料，其成分以及生物力学作用与骨组织相接近，将其作为研究对象应用于骨修复材料有很好的前景。重组人骨形态发生蛋白2（recombinant human bone morphogenetic protein 2，rhBMP-2）是目前已知的促进骨折愈合的生长因子，在骨修复材料中的应用也相当广泛。本文就珍珠粉、rhBMP-2 以及其复合物目前在骨组织修复中的应用研究进展进行系统综述。同时还分析了材料所存在的问题，展望了该复合材料的应用前景。

关键词: 珍珠粉, rhBMP-2, 组织工程, 植骨材料

CLC Number:

R782.4

LI Na, CHEN Zhuo-geng, XU Pu. Recent Advance on the Application of Pearl Powder，rhBMP-2 and their Complex in Bone Engineering[J]. 《Journal of Oral and Maxillofacial Surgery》, doi: 10.3969/j.issn.1005-4979.2018.03.011.

李娜，陈灼庚（综述），徐普（校审）. 珍珠粉、rhBMP-2及其复合物在骨组织修复中的应用研究进展[J]. 《口腔颌面外科杂志》, doi: 10.3969/j.issn.1005-4979.2018.03.011.

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URL: https://journal06.magtech.org.cn/Jweb_joms/EN/10.3969/j.issn.1005-4979.2018.03.011

https://journal06.magtech.org.cn/Jweb_joms/EN/Y2018/V28/I3/176

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