Abstract:

Periodontitis is a chronic inflammatory disease affecting periodontal supporting tissues, which is closely associated with various systemic diseases. In recent years, a number of epidemiological investigations have revealed the possible independent association between periodontitis and myocardial infarction to some extent, and certain research results suggest that periodontal pathogens may be one of the important factors mediating this association. Based on the current research data, the link between the two diseases has yet to be established. This article reviews the research progress on the association between periodontitis and myocardial infarction, with the aim of evaluating the existing epidemiological evidence, elucidating potential pathological mechanisms, and providing a theoretical basis for interdisciplinary prevention and treatment strategies.

Key words: periodontitis, myocardial infarction, cardiovascular disease, Porphyromonas gingivalis

摘要：

牙周炎是一种累及牙周支持组织的慢性炎症，与多种全身性疾病关系密切。近年来，多项流行病学调查提示牙周炎与心肌梗死之间可能存在独立的关联，部分研究结果表明牙周致病菌或许是介导这种关联的重要因素之一。基于目前的研究数据，二者的相关性仍待明确，本文就牙周炎与心肌梗死相关性的研究进展作一综述，以期评估现有流行病学证据，梳理其潜在病理机制，为跨学科防治策略提供理论依据。

关键词: 牙周炎, 心肌梗死, 心血管疾病, 牙龈卟啉单胞菌