Regulation effects of inflammasomes on periodontitis and atherosclerosis

doi:10.12439/kqhm.1005-4979.2026.05.008

Abstract

Abstract:

Inflammasomes are cytoplasmic supramolecular complexes, important components of the body's innate immune system, playing an important role in recognizing exogenous microbial invasion or endogenous damage signals. Periodontitis and atherosclerosis are both chronic inflammatory diseases, and the association between them has attracted increasing attention. Inflammasomes play important regulatory roles in the development and progression of systemic inflammatory diseases. This article reviews the key inflammasomes and their regulatory mechanisms, which play vital roles in periodontitis and atherosclerosis.

Key words: inflammasome, periodontitis, atherosclerosis

摘要：

炎症小体（inflammasomes）是一种细胞质超分子复合物，作为机体先天免疫的重要组成部分，在识别外源性微生物的入侵或内源性损伤中发挥重要作用。牙周炎与动脉粥样硬化均为慢性炎症性疾病，二者之间的关联性日益受到关注。炎症小体在全身炎症性疾病的发生、发展中具有重要的调控作用，本文将综述在牙周炎与动脉粥样硬化中发挥重要作用的关键炎症小体及其调控作用。

关键词: 炎症小体, 牙周炎, 动脉粥样硬化

CLC Number:

R781.4

SHEN Ziyun, WANG Zuolin. Regulation effects of inflammasomes on periodontitis and atherosclerosis[J]. Journal of Oral and Maxillofacial Surgery(CN), 2026, 36(5): 416-419.

沈紫芸, 王佐林. 炎症小体在牙周炎与动脉粥样硬化中的调控作用[J]. 《口腔颌面外科杂志》, 2026, 36(5): 416-419.

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URL: https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2026.05.008

https://journal06.magtech.org.cn/Jweb_joms/EN/Y2026/V36/I5/416

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