摘要：
目的： 探讨鼻型结外NK/T细胞淋巴瘤（extranodal NK/T-cell lymphoma of nasal type，ENKTL-NT）的临床病理特点、诊断及治疗，为临床医生的诊治提供参考。方法： 报告1例以上腭黏膜呈中线对称溃疡为主要症状的ENKTL-NT病例，并结合文献进行讨论分析。结果： 于我院多次活检明确诊断后，通过联合治疗，患者病情明显好转，术后随访9个月，患者死亡。结论： ENKTL-NT在临床上较少见且临床特征复杂，即使结合组织活检往往也难以明确诊断。对于长期不愈的口腔溃疡应保持高度警惕，推荐采用多处重复活检策略以提升诊断准确性。
关键词:
鼻型结外NK/T细胞淋巴瘤,
口腔溃疡,
诊治
Abstract:
Objective: To investigate the clinicopathological features, diagnosis and treatment of extranodal NK/T-cell lymphoma of nasal type (ENKTL-NT), and to provide reference for the diagnosis and treatment of clinicians.Methods: A case of palatal mucosa with a midline symmetry ulcer was followed up and ENKTL-NT was discussed, and analyzed in combination with literature.Results: After multiple biopsies were taken and the diagnosis was confirmed, the patient's condition was obviously improved by combined treatment. During nine months of postoperative follow-up, the patient died.Conclusion: ENKTL-NT is rare for stomatologists, and its clinical features are complex. Biopsy is often difficult to confirm the diagnosis. It is necessary to implement repeated multi-site biopsy strategies to improve diagnostic accuracy.
Key words:
extranodal NK/T-cell lymphoma of nasal type,
oral ulcer,
diagnosis and treatment
中图分类号:
于栋林, 曹璋, 王文龙, 马向瑞, 唐娟, 左金华. 以中线对称口腔溃疡为主要症状的鼻型结外NK/T细胞淋巴瘤1例报告及文献复习[J]. 《口腔颌面外科杂志》, 2025, 35(2): 157-159.
YU Donglin, CAO Zhang, WANG Wenlong, MA Xiangrui, TANG Juan, ZUO Jinhua. Extranodal NK/T-cell lymphoma of nasal type with midline symmetry oral ulcer as the main symptom: A case report and literature review[J]. 《Journal of Oral and Maxillofacial Surgery》, 2025, 35(2): 157-159.