摘要：

目的：回顾性分析168例下颌下腺肿瘤（submandibular gland tumors，SGT）患者的临床病理学资料，为该病的早期诊断和治疗提供帮助。方法：收集2011年—2018年间南昌大学第一附属医院口腔颌面外科收治的168例下颌下腺肿瘤患者的临床资料，分析该病的发病特征及临床诊断。结果：男性69例，女性99例，男女比例为0.69∶1；良性上皮性肿瘤128例（76.19%），恶性上皮性肿瘤40例（23.81%），良、恶性上皮性肿瘤的比例为3.2∶1；多形性腺瘤在良性上皮性肿瘤中占比最大，腺样囊性癌、鳞状细胞癌、黏液表皮样癌、涎腺导管癌在恶性上皮性肿瘤中分别排在前4位。B超、CT、细针吸取细胞学及术中冰冻切片对肿瘤良、恶性判断与病理诊断的符合率分别为43.10%、42.86%、82.26%及98.42%。结论：下颌下腺良性上皮性肿瘤发生率高于恶性上皮性肿瘤；最常见的下颌下腺良性肿瘤是多形性腺瘤，最常见的下颌下腺恶性肿瘤是腺样囊性癌；细针吸取细胞学检查在下颌下腺肿瘤的术前诊断方面具有价值。

关键词: 下颌下腺, 肿瘤, 组织病理学, 临床资料

Abstract:

Objective: To analyze the clinicopathological data of 168 patients with submandibular gland tumors （SGT） and provide help for the early diagnosis and treatment of this kind of disease. Methods: The clinical and pathological data of 168 patients with SGT treated between 2011 and 2018 at the department of oral and maxillofacial surgery of the First Affiliated Hospital of Nanchang University were retrospectively analyzed. Results: There were 69 male cases and 99 female cases, the ratio of gender was 0.69∶1. 128 cases were benign epithelial tumors (76.19%), 40 cases were malignant epithelial tumors (23.81%), and the proportion of benign versus malignant epithelial tumors was 3.2∶1. Pleomorphic adenoma was the mostly encountered of benign epithelial tumor, adenoid cystic carcinoma, squamous cell carcinoma, mucoepidermoid carcinoma and salivary duct carcinoma were the mostly encountered of four types of malignant epithelial tumors. The preoperative diagnostic accuracy rate with B-mode ultrasound was 43.10%, CT was 42.86%, fine needle aspiration cytology was 82.26% and interoperative frozen section biopsy was 98.42% respectively. Conclusions: Among submandibular gland tumors, benign epithelial tumors are more common than malignant ones. Pleomorphic adenoma and adenoid cystic carcinoma are the most common benign and malignant epithelial tumors respectively. Fine needle aspiration cytology is more valuable in preoperative diagnosis of SGT.

Key words: submandibular gland, tumor, histopathology, clinical date

中图分类号: 

• R782

• R739.8