摘要：
目的：探讨颈动脉体瘤（carotid body tumor，CBT）术后发生缺血性脑卒中（ischemic stroke，IS）的危险因素。方法：回顾性分析2006年2月—2018年7月收治的43例CBT患者的临床资料，记录患者的瘤体直径、手术时间、术中出血量、术中血管损伤情况等。根据患者术后是否发生IS将患者分为2组。分析2组间临床资料的差异，并运用多因素logistic分析CBT术后发生IS的危险因素。结果：与术后未发生IS的患者（未发生组）相比，IS组（5例，11.6%）的手术时间更长（P<0.001），瘤体直径更大（P<0.001），术中出血量更多（P<0.001），颈内、外动脉损伤更常见（P<0.05）。2组间年龄、性别、瘤体侧别差异均无统计学意义（P>0.05）。logistic回归分析结果显示，瘤体直径是术后发生IS的独立危险因素（OR=3.13, 95%CI=1.71~302.12，P=0.018）。结论：CBT术后IS的发生与瘤体直径、术中出血量、手术时间、颈内和颈外动脉损伤呈正相关，瘤体直径是术后发生IS的独立危险因素。
关键词:
颈动脉体瘤,
缺血性脑卒中,
危险因素,
外科治疗
Abstract:
Objective: To investigate the risk factors of ischemic stroke(IS) after surgery for carotid body tumor (CBT). Methods: The clinical data of 43 CBT patients admitted from February 2006 to July 2018 were retrospectively analyzed, and the tumor size, operation time, intraoperative blood loss and intraoperative vascular injuries of the patients were recorded. Patients were divided into two groups according to whether IS occurred after surgery. The differences of clinical data between the two groups were analyzed, and the risk factors of IS after surgery for CBT were analyzed using multivariate logistic analysis. Results: In the IS group (5 cases, 11.6%), the duration of surgical operation was longer (P<0.001), the tumor size was larger (P<0.001), there was more intraoperative blood loss (P<0.001), and the internal and external carotid artery injuries were more common (P<0.05) than those without IS. There were no statistically significant differences in age, gender and tumor location side between the two groups(P>0.05). Logistic regression analysis showed that tumor size was an independent risk factor for postoperative IS(OR=3.13, 95%CI=1.71-302.12, P=0.018). Conclusion: The occurrence of IS after surgery for CBT is positively correlated with the diameter of the tumor, intraoperative blood loss, operation time, and internal and external carotid artery injuries. The diameter of the tumor is an independent risk factor for the occurrence of IS after surgery for CBT.
Key words:
carotid body tumor,
ischemic stroke,
risk factors,
surgical treatment
中图分类号:
牟思琦, 丁明超, 吴中明, 张浩, 魏建华, 王维戚. 颈动脉体瘤术后发生缺血性脑卒中危险因素的回顾分析[J]. 《口腔颌面外科杂志》, 2021, 31(3): 163-167.
MU Siqi, DING Mingchao, WU Zhongming, ZHANG Hao, WEI Jianhua, WANG Weiqi. A retrospective analysis of the risk factors for ischemic stroke after operation of carotid body tumor[J]. 《Journal of Oral and Maxillofacial Surgery》, 2021, 31(3): 163-167.