摘要： 目的：探讨与口腔颌面部非霍奇金淋巴瘤确诊相关的临床病理特点。方法：对2000?-02—2012-03郑州大学附属洛阳市中心医院口腔颌面外科收治的17例非霍奇金淋巴瘤，进行回顾性临床病理分析。结果：口腔颌面部非霍奇金淋巴瘤可发生于任何年龄，男女之比为2.4∶1，可发生于颈部及颌下区、牙龈、腭部、腮腺、颊部及舌根部等。病理类型以B细胞淋巴瘤多见。临床及病理首诊确诊率均偏低。结论：口腔颌面部非霍奇金淋巴瘤临床表现多样，确诊依靠病理学诊断，但对取检标本及病理诊断均有较高要求，有些不典型病例需进行分子生物学检测及严密随访。
关键词:
口腔颌面部,
淋巴瘤,
临床病理
Abstract: Objective: To summarize the clinical pathology and definite diagnosis of non-Hodgkin′s lymphoma(NHL) in oral and head region. Methods:17 cases with NHL admitted in Luoyang Central Hospital during 2000-02 to 2012-03 were retrospectively reviewed. Results: The patients with NHL have a wide range of age. Males are more than females, the ratio is 2.29∶1. The lesion located in cervical part, submaxillary region, gum, hard or soft palate, parotid gland, buccal area, and the base of tongue. The pathological diagnosis were mainly B cell lymphoma. The definite diagnosis rate was low during first visit. Conclusion: Clinical manifestations of oral-maxillofacial of non-Hodgkin′s lymphomas varied differently, higher requirements are needed in biopsy and pathology examination. Molecular biological detection and close follow-up study is needed in some atypical cases.
Key words:
oral and maxillofacial region,
lymphoma,
clinicopathology
中图分类号:
侯卫锋，郭海山，李军红. 口腔颌面部非霍奇金淋巴瘤临床病理分析[J]. 《口腔颌面外科杂志》, 2013, 23(1): 50-53.
HOU Wei-feng, GUO Hai-shan, LI Jun-hong. Clinicopathology of non-Hodgkin′s Lymphoma in Oral and Maxillofacial Region[J]. 《Journal of Oral and Maxillofacial Surgery》, 2013, 23(1): 50-53.