Roles of BMPs in the Osteogenesis of Adipose-Derived Stem Cells

doi:10.3969/j.issn.1005-4979.2015.05.016

Abstract

Abstract: Adipose tissue-derived stem cells（ADSCs） have potential of differentiating to osteogenesis. During the process, BMPs have synergistic effects to promote the mesenchymal stem cells to osteogenesis differentiation through BMPs signaling. However, it remains unclear how the pleiotropic BMPs control osteogenic commitment of ADSCs. Various active agents and methods have been used to enhance and accelerate the osteogenesis of ADSCs through promoting BMP signaling. In this review, we focus on the roles of BMPs in the osteogenesis of ADSCs.

Key words: BMPs, adipose tissue-derived stem cells, osteogenesis

摘要： 脂肪干细胞（ADSCs）具有成骨分化潜能，BMPs可以通过其信号通路产生协同作用。然而，BMPs信号在ADSCs成骨过程中作用机理尚不明确。通过增强BMPs信号，研究人员可运用多种方法促进脂肪干细胞向成骨方向分化。本文将BMPs在脂肪干细胞成骨分化中的作用进行综述。

关键词: BMPs； , 脂肪干细胞； , 骨生成

CLC Number:

R782.4

LI Chao-yuan, WANG Zuo-lin. Roles of BMPs in the Osteogenesis of Adipose-Derived Stem Cells[J]. 《Journal of Oral and Maxillofacial Surgery》, 2015, 25(5): 383-.

厉超元（综述）王佐林（审校）. BMPs对脂肪干细胞成骨分化作用的研究进展[J]. 《口腔颌面外科杂志》, 2015, 25(5): 383-.

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URL: https://journal06.magtech.org.cn/Jweb_joms/EN/10.3969/j.issn.1005-4979.2015.05.016

https://journal06.magtech.org.cn/Jweb_joms/EN/Y2015/V25/I5/383

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