外周型骨化性纤维瘤1例报道及文献复习

doi:10.3969/j.issn.1005-4979.2022.05.011

《口腔颌面外科杂志》 ›› 2022, Vol. 32 ›› Issue (5): 324-327. doi: 10.3969/j.issn.1005-4979.2022.05.011

• 病例报告 • 上一篇

外周型骨化性纤维瘤1例报道及文献复习

杨成瑙¹(), 孙鹏峰¹, 张佳², 段嘉峰³, 刘红生¹()

1.西安市中心医院放射科，陕西西安 710003
2.西安交通大学口腔医院病理科，陕西西安 710003
3.西安交通大学口腔医院头颈肿瘤外科，陕西西安 710003

收稿日期:2021-05-20 修回日期:2022-09-17 出版日期:2022-10-28 发布日期:2022-10-31
通讯作者: 刘红生，副主任医师. E-mail: lhs841209@163.com
作者简介:
杨成瑙（1993—），女，青海人，住院医师，硕士研究生. E-mail: 1095508672@qq.com

Peripheral ossifying fibroma: A case report and literature review

YANG Chengnao¹(), SUN Pengfeng¹, ZHANG Jia², DUAN Jiafeng³, LIU Hongsheng¹()

1. Department of Radiology, Hospital of Stomatology, Xi′an Jiaotong University, Xi′an Central Hospital, Xi′an 710003, Shaanxi Province
2. Department of Oral Pathology, Hospital of Stomatology, Xi′an Jiaotong University, Xi′an 710003, Shaanxi Province, China
3. Department of Head and Neck Oncology Surgery, Hospital of Stomatology, Xi′an Jiaotong University, Xi′an 710003, Shaanxi Province, China

Received:2021-05-20 Revised:2022-09-17 Online:2022-10-28 Published:2022-10-31

摘要/Abstract

摘要：

外周型骨化性纤维瘤（peripheral ossifying fibroma，POF）发病相对罕见，临床上易被误诊。本文报道1例经手术病理证实的腭部POF，并复习相关文献，对该病临床病理、影像学表现及相关鉴别诊断等进行讨论。

关键词: 外周型骨化性纤维瘤, 影像学特征, 鉴别诊断

Abstract:

Peripheral ossifying fibroma(POF) is a rare benign tumor that can be easily misdiagnosed in clinic. We report a pathologically confirmed case of POF in the palate. The pathological features, imaging features, and differential diagnoses were discussed by reviewing the relevant literatures.

Key words: peripheral ossifying fibroma, image manifestation, differential diagnoses

中图分类号:

R782

杨成瑙, 孙鹏峰, 张佳, 段嘉峰, 刘红生. 外周型骨化性纤维瘤1例报道及文献复习[J]. 《口腔颌面外科杂志》, 2022, 32(5): 324-327.

YANG Chengnao, SUN Pengfeng, ZHANG Jia, DUAN Jiafeng, LIU Hongsheng. Peripheral ossifying fibroma: A case report and literature review[J]. 《Journal of Oral and Maxillofacial Surgery》, 2022, 32(5): 324-327.

https://journal06.magtech.org.cn/Jweb_joms/CN/Y2022/V32/I5/324

图/表 2

图1 OF在口腔及CT中的表现 A. 肉眼可见口腔内腭部偏左侧一粉红色肿物，边界清楚；B—D. 轴位、冠状位及矢状位CT图像。

Figure 1 Photograph and CT manifestations of OF in the palate

图2 术后病理结果 A. 肿物被覆复层鳞状上皮，局部溃疡形成，下方为纤维组织增生，其间可见大小不等的牙骨质小体（×40）；B. 纤维组织间质中可见骨小梁样的骨组织形成（×100）。

Figure 2 Postoperative histopathological results of POF

参考文献 14

[1]	McCarthy EF. Fibro-osseous lesions of the maxillofacial bones[J]. Head Neck Pathol, 2013, 7(1): 5-10. doi: 10.1007/s12105-013-0430-7 pmid: 23459840
[2]	Vlachou S, Terzakis G, Doundoulakis G, et al. Ossifying fibroma of the temporal bone[J]. J Laryngol Otol, 2001, 115(8): 654-656. pmid: 11535150
[3]	Parvizi F, Rout PG. An ossifying fibroma presenting as Stafne′s idiopathic bone cavity[J]. Dentomaxillofac Radiol, 1997, 26(6): 361-363. doi: 10.1038/sj.dmfr.4600294 URL
[4]	Brademann G, Werner JA, Jänig U, et al. Cemento-ossifying fibroma of the petromastoid region: Case report and review of the literature[J]. J Laryngol Otol, 1997, 111(2): 152-155. doi: 10.1017/s0022215100136709 pmid: 9102442
[5]	Wakefield MJ, Ross AH, Damato EM, et al. Review of lateral orbital wall ossifying fibroma[J]. Orbit, 2010, 29(6): 317-320. doi: 10.3109/01676830.2010.522299 pmid: 21158572
[6]	Mergoni G, Meleti M, Magnolo S, et al. Peripheral ossifying fibroma: A clinicopathologic study of 27 cases and review of the literature with emphasis on histomorphologic features[J]. J Indian Soc Periodontol, 2015, 19(1): 83-87. doi: 10.4103/0972-124X.145813 pmid: 25810599
[7]	王婷婷, 黄永松, 徐丽, 等. 颌骨骨化纤维瘤28例临床及病理学分析[J]. 口腔颌面外科杂志, 2017, 27(5): 321-326.
[8]	范鑫, 刘柳恒, 杜金超, 等. 腮腺区骨化性纤维瘤1例[J]. 医学影像学杂志, 2020, 30(9): 1652, 1656.
[9]	Okui T, Ibaragi S, Ono K, et al. Surgical resection of a giant peripheral ossifying fibroma in mouth floor managed with fiberscopic intubation[J]. Clin Case Rep, 2021, 9(1): 180-184. doi: 10.1002/ccr3.v9.1 URL
[10]	Lázare H, Peteiro A, Pérez Sayáns M, et al. Clinicopathological features of peripheral ossifying fibroma in a series of 41 patients[J]. Br J Oral Maxillofac Surg, 2019, 57(10): 1081-1085. doi: S0266-4356(19)30390-0 pmid: 31601435
[11]	Baněčková M, Agaimy A. SATB2 is frequently expressed in ossifying and non-ossifying peripheral oral fibroma of the gingival region but not in reactive fibromatous lesions from other intraoral sites[J]. Ann Diagn Pathol, 2020, 46: 151510. doi: 10.1016/j.anndiagpath.2020.151510 URL
[12]	温晓玲, 伍东升, 张洪静, 等. 颌骨良性肿瘤和瘤样病变的多层螺旋CT表现及其病理基础[J]. 重庆医学, 2018, 47(24): 3223-3226.
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