《口腔颌面外科杂志》 ›› 2016, Vol. 26 ›› Issue (6): 431-. doi: 10.3969/j.issn.1005-4979.2016.06.011

• 临床总结 • 上一篇    下一篇

硫酸钙、β-TCP及生物活性玻璃治疗颌骨囊肿的疗效观察

王珊珊,程继光,徐文华,陈新,周健   

  1. 安徽医科大学口腔医学院,安徽医科大学附属口腔医院,安徽省口腔疾病研究中心实验室
  • 收稿日期:2016-08-17 修回日期:2016-12-06 出版日期:2016-12-28 发布日期:2017-06-30
  • 通讯作者: 周健,教授. E-mail: zj@ahmu.edu.cn E-mail:zj@ahmu.edu.cn
  • 作者简介:王珊珊(1991—),女,安徽人,医师,硕士研究生. E-mail: 1157719414@qq.com
  • 基金资助:

    国家自然科学基金面上项目(81070864)

Comparison of Medical Calcium, β-tricalcium Phosphate, and Perioglas in the treatment of Odontogenic Cystic Cavities

WANG Shan-shan, CHENG Ji-guang, XU Wen-hua, CHEN Xin, ZHOU Jian   

  1. Stomatology Hospital and College, Anhui Medical University, Key Lab of Oral Diseases Research of Anhui Province
  • Received:2016-08-17 Revised:2016-12-06 Online:2016-12-28 Published:2017-06-30

摘要: 目的:观察硫酸钙、β-TCP(β-磷酸三钙)及生物玻璃(倍骼生)在颌骨囊肿治疗中的疗效。方法:颌骨囊肿病例45例,行囊肿刮除术后,随机分为4组,骨腔内填充不同物质。A组:硫酸钙组;B组:β-TCP组;C组:生物玻璃(倍骼生)组;D组:空白组。术后观察患者术区肿胀程度,且1、3、6、12个月后拍摄CBCT或全景片,观察术区骨愈合情况。结果:A组患者术后1周内术区肿胀明显; A、C组患者6个月后,术区与正常骨组织无明显区别;B组患者12个月后,新骨几乎充填整个骨腔;D组新骨形成明显较A、B、C组慢。结论:在新骨形成方面,A、B、C组分别与D组相比,差异均有统计学意义;硫酸钙会引起部分患者术区肿胀反应。

关键词:  硫酸钙, β-TCP, 倍骼生, 颌骨囊肿, 骨缺损修复

Abstract: Objective: To observe the different effect of medical calcium,β-tricalcium phosphate(β-TCP)and Perioglas in the treatment of odontogenic cysts cavities. Methods: Screen 45 cases of jaw cyst randomly. After cyst curettage operation, according to the different bone cavity filling materials, these cases divided into four groups, Group A: Medical calcium; Group B: Calcium phosphate; Group C: Perioglas; Group D: Blank group. Observations included the swelling degree of surgical site; Regular x-ray examination was performed at 1, 3, 6, 12 months intervals to realise the bone regeneration. Results: In group A, the swelling of surgical site was obvious after operation. In group A and group C, after 6 months of operation, there was no significant difference between the operative region and surrounding normal bone tissue. Group B: 12 months later, the material was completely absorbed, and the new bone was almost filled with the whole bone cavity. Group D: The rate of the new bone formation was significantly retarded  than that of A, B, and C groups. Conclusion: Comparison between group A, B, C and group D, the rate of new bone formation differed significantly. Medical calcium sulfate could cause swelling reaction in the operation area.

Key words: Medical calcium sulfate, β-tricalcium phosphate, Perioglas, jaw cyst, bone defect repair

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