Abstract:  Objective:  To review and summarize the clinical experience and understanding on the diagnosis and treatment of histiocytic necrotizing lymphadenitis.  Methods: 19  patients (8 male and 11 female)， whose pathological diagnosis were histiocytic necrotizing lymphadenitis， were retrospectively analyzed. Age group was 19~45 years, with a mean of 22 years. Course of disease lasted from 2 weeks to 3 months. Variable numbers of cervical lymph nodes adenopathy was the most prominent syndrome. Hormone therapy was the first choice. Results: 19 cases of histiocytic necrotizing lymphadenitis patients with cervical lymphadenopathy were improved after hormone therapy, 15 patients with fever and elevated ESR, 13 cases with leucopenia included. Conclusion: Young person with unexplained cervical lymphadenopathy, fever, leukopenia, ESR, invalid with antibiotic therapy and effective response to hormone therapy can be used as the main reference for the diagnosis of histiocytic necrotizing lymphadenitis.

Key words: 组织细胞坏死性淋巴结炎, 临床特点, 诊断

摘要： 目的：分析总结组织细胞坏死性淋巴结炎患者具有诊断意义的临床特点，提高该病临床诊断的准确率，减少误诊。方法：对经病理证实为组织细胞坏死性淋巴结炎患者的临床表现进行分析，总结出该疾病的临床特点。结果：19例组织细胞坏死性淋巴结炎患者，均有颈部淋巴结肿大，均经激素治疗后有效。15例临床有发热症状、血沉增快，13例白细胞减少。结论：不明原因的颈部淋巴结肿大、发热，但抗生素无效，激素治疗好转，伴有白细胞减少、血沉加快，可作为组织细胞坏死性淋巴结炎临床诊断的主要参考依据，能够提高该病临床诊断的准确率。

关键词: 组织细胞坏死性淋巴结炎, 临床特点, 诊断

CLC Number: 

•  

• R