Recent Advances in Single Cell RNA-Seq and its Application in the Studies of Mesenchymal Stem Cell Research

doi:10.3969/j.issn.1005-4979.2019.03.010

Abstract

Abstract: Department of Implantology, School and Hospital of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072,China

Key words: single cell RNA-Seq, mesenchymal stem cells, stem cell heterogeneous

摘要： 单细胞转录组测序技术可在单个细胞水平上定量分析细胞间的基因表达差异。随着该技术的迅速发展，高通量单细胞转录组测序的出现可实现数千个细胞的同时测序，使群体细胞的异质性分析更加高效。间充质干细胞是具有异质性的干细胞群体，这种异质性使干细胞治疗的临床应用变得复杂。此篇综述讨论了单细胞转录组测序的技术发展及其在间充质干细胞研究中的应用现状。

关键词: 单细胞转录组测序； , 间充质干细胞； , 干细胞异质性

CLC Number:

R782.4

SUN Rui nan, WANG Zuo lin. Recent Advances in Single Cell RNA-Seq and its Application in the Studies of Mesenchymal Stem Cell Research[J]. 《Journal of Oral and Maxillofacial Surgery》, doi: 10.3969/j.issn.1005-4979.2019.03.010.

孙睿男，王佐林. 单细胞转录组测序技术进展及其在间充质干细胞研究中的应用#br#[J]. 《口腔颌面外科杂志》, doi: 10.3969/j.issn.1005-4979.2019.03.010.

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URL: https://journal06.magtech.org.cn/Jweb_joms/EN/10.3969/j.issn.1005-4979.2019.03.010

https://journal06.magtech.org.cn/Jweb_joms/EN/Y2019/V29/I3/174

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