Applications of Cell Membrane-Coated Nanoparticles in the Treatment of Oral Diseases

Abstract

Abstract:

Cell membrane-coated nanoparticles (CMCNPs) are a class of nanoscale carriers enveloped by natural cell membranes, which efficiently preserve the abundant functional proteins and receptors on the surface of cell membranes, thereby integrating the biological properties of natural cell membranes and demonstrating excellent biocompatibility and precise targeting ability in the field of biomedicine. In treating various oral diseases, such as oral cancer and periodontitis, CMCNPs have shown great potential and provide new research directions for overcoming oral medicine problems, emerging as one of the forefront topics in current biomedical research. This paper focuses on CMCNPs, presenting a detailed review of their preparation techniques and research progress in treating oral diseases. This article focuses on CMCNPs and deeply explores relevant mechanisms, application results and existing challenges, aiming to provide scientific and precise references for the subsequent academic research and clinical translation of oral diseases such as oral cancer, periodontitis, and oral mucosal diseases.

Key words:

cell membrane-coated nanoparticles, oral cancer, periodontitis

摘要：

细胞膜包被纳米颗粒（cell membrane-coated nanoparticles，CMCNPs）是一类利用天然细胞膜包裹的纳米级载体，能够高效保留细胞膜表面丰富的功能蛋白及受体，从而整合天然细胞膜的生物学特性，在生物医学领域彰显出卓越的生物相容性和精准的靶向能力。在口腔癌、牙周炎等多种口腔疾病的治疗中，CMCNPs显示出巨大的应用潜能，为攻克口腔医学难题提供了新的研究方向，已成为当下生物医学研究的前沿热点之一。本文聚焦于CMCNPs，深入探讨相关机制、应用成果及现存挑战，旨在为口腔癌、牙周炎、口腔黏膜病等口腔疾病的学术研究及临床转化提供科学、精准的参考依据。

关键词:

细胞膜包被纳米颗粒, 口腔癌, 牙周炎

CLC Number:

R782

ZHANG Zhanwei, YU Yiqiang, SU Jiansheng.

Applications of Cell Membrane-Coated Nanoparticles in the Treatment of Oral Diseases[J]. 《Journal of Oral and Maxillofacial Surgery》.

张湛玮, 俞懿强, 苏俭生.

细胞膜包被纳米颗粒在口腔疾病治疗中的研究进展[J]. 《口腔颌面外科杂志》.

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