miR-146a在相关自身免疫性疾病中的研究进展

doi:10.3969/j.issn.1005-4979.2013.04.017

《口腔颌面外科杂志》 ›› 2013, Vol. 23 ›› Issue (4): 305-308. doi: 10.3969/j.issn.1005-4979.2013.04.017

miR-146a在相关自身免疫性疾病中的研究进展

石欢（综述）俞创奇，张建军，郑凌艳（审校）

上海交通大学医学院附属第九人民医院·口腔医学院口腔颌面外科，上海市口腔医学重点实验室，上海 200011

出版日期:2013-08-28 发布日期:2013-11-07
通讯作者: 俞创奇，教授. E-mail:ycq616@hotmail.com
作者简介:石欢（1987—），女，湖南湘潭人，硕士研究生. E-mail:shihuan1312@163.com
基金资助:
国家自然科学基金资助项目(81100766)；上海市学科建设项目（S30206）

Advances of miR-146a in the Pathogenesis of Relevant Autoimmune Diseases

SHI Huan，YU Chuang-qi，ZHANG Jian-jun，ZHENG ling-yan

Department of Oral and Maxillofacial Surgery，College of Stomatology，the Ninth People’s Hospital，School of Medicine，Shanghai Jiaotong University，Shanghai Key Laboratory of Stomatology，
Shanghai 2012，China

Online:2013-08-28 Published:2013-11-07

摘要/Abstract

关键词: miR-146a, 自身免疫, 类风湿, 红斑狼疮, 舍格伦, 发病机制

Key words: , miR-146a；autoimmunity；rheumatoid arthritis；systemic lupus erythematosus；Sjogren&rsquo, s syndrome；pathogenesis

中图分类号:

R781.71

石欢（综述）俞创奇，张建军，郑凌艳（审校）. miR-146a在相关自身免疫性疾病中的研究进展[J]. 《口腔颌面外科杂志》, 2013, 23(4): 305-308.

SHI Huan，YU Chuang-qi，ZHANG Jian-jun，ZHENG ling-yan. Advances of miR-146a in the Pathogenesis of Relevant Autoimmune Diseases[J]. 《Journal of Oral and Maxillofacial Surgery》, 2013, 23(4): 305-308.

https://journal06.magtech.org.cn/Jweb_joms/CN/Y2013/V23/I4/305

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[18] Chatzikyriakidou A, Voulgari PV, Georgiou I, et al. A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility[J]. Joint Bone Spine 2010,77(5):411-413.

[19] Lee PY, Li Y, Richards HB, et al. Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus[J]. Arthritis Rheum, 2007,56(11):3759-3769.

[20] Luo X, Yang W, Ye DQ, et al. A functional variant in MicroRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus[J]. PLoS Genet, 2011,7(6):e1002128.

[21] Arao TG, Guimaraes AL, de Paula AM, et al. Increased miRNA-146a and miRNA-155 expressions in oral lichen planus[J]. Arch Dermatol Res, 2012, 304(5):371-375.

[22] Shulze-Koops H, Kalden JR. The balance of Th1／Th2 cytokines in rheumatoid arthritis [J]. Best Pract Res Clin Rheumatol, 2001, 15(5):677-691.

[23] 俞创奇, 胡北平, 丁永敏，等. 85例舍格伦综合征腮腺表现的临床分析与探讨[J]. 口腔颌面外科杂志, 2000, 10(1):5-7.

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