《口腔颌面外科杂志》 ›› 2021, Vol. 31 ›› Issue (4): 245-248. doi: 10.3969/j.issn.1005-4979.2021.04.9

• 综述 • 上一篇    下一篇

颞下颌关节骨关节炎发病机制的研究进展

钟阳(), 满城()   

  1. 遵义医科大学附属口腔医院口腔颌面创伤及正颌外科,贵州 遵义 563000
  • 收稿日期:2020-07-21 修回日期:2021-01-26 出版日期:2021-08-28 发布日期:2021-11-03
  • 通讯作者: 满 城, 副教授. E-mail:mancheng1106@163.com
  • 作者简介:

    钟 阳(1993—),男,四川人,硕士研究生,E-mail:

Recent advances on the pathogenesis of TMJ osteoarthritis

ZHONG Yang(), MAN Cheng()   

  1. Department of Oral and Maxillofacial Orthognathic Surgery, Stomatological Hospital, Zunyi Medical University, Zunyi 563000, Guizhou Province, China
  • Received:2020-07-21 Revised:2021-01-26 Online:2021-08-28 Published:2021-11-03

摘要:

颞下颌关节骨关节炎(temporomandibular joint osteoarthritis, TMJOA)是一种关节的慢性、退行性病变,可引起颞下颌关节的剧烈疼痛和功能障碍。其主要病理特征是进行性软骨退化、软骨下骨重塑和滑膜组织的慢性炎症。目前颞下颌关节骨关节炎的确切发病机制和过程尚不清楚,但对于其发病机制的研究较多,本文对近年来颞下颌关节骨性关节炎发病机制研究的最新进展进行综述。

关键词: 颞下颌关节, 骨关节炎, 发病机制, 研究进展

Abstract:

Temporomandibular joint osteoarthritis(TMJOA) is a common disease that can cause severe pain and dysfunction. TMJOA pathology is characterized by progressive cartilage degradation, subchondral bone remodeling, and chronic inflammation in the synovial tissue. At present, the exact pathogenesis and process of TMJOA is unclear. This review summarizes the current understanding of mechanisms underlying the pathogenesis of TMJOA.

Key words: temporomandibular joint, osteoarthritis, pathogenesis, research progress