[1] Castro-Govea Y, Cervantes-Kardasch VH, Borrego-Soto G, et al. Human bone morphogenetic protein 2-transduced mesenchymal stem cells improve bone regeneration in a model of mandible distraction surgery[J]. J Craniofac Surg, 2012,23(2):392-396.
[2] Long J, Li P, Du HM, et al. Effects of bone morphogenetic protein 2 gene therapy on new bone formation during mandibular distraction osteogenesis at rapid rate in rabbits[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2011,112(1):50-57.
[3] Kroczek A, Park J, Birkholz T, et al. Effects of osteoinduction on bone regeneration in distraction: results of a pilot study[J]. J Craniomaxillofac Surg, 2010,38(5):334-344.
[4] Hu J, Qi M C, Zou SJ, et al. Callus formation enhanced by BMP-7 ex vivo gene therapy during distraction osteogenesis in rats[J]. J Orthop Res, 2007,25(2):241-251.
[5] Li J, Li Y, Ma S, et al. Enhancement of bone formation by BMP-7 transduced MSCs on biomimetic nano-hydroxyapatite/polyamide composite scaffolds in repair of mandibular defects[J]. J Biomed Mater Res A, 2010,95(4):973-981.
[6] Fierro F A, Kalomoiris S, Sondergaard CS, et al. Effects on proliferation and differentiation of multipotent bone marrow stromal cells engineered to express growth factors for combined cell and gene therapy[J]. Stem Cells, 2011,29(11):1727-1737.
[7] 贺维,倪小兵,解龙川,等. bFGF基因修饰的BMSCs促进大鼠下颌牵引成骨的研究[J]. 临床口腔医学杂志, 2010,26(11):655-658.
[8] Jiang X, Zou S, Ye B, et al. bFGF-Modified BMMSCs enhance bone regeneration following distraction osteogenesis in rabbits[J]. Bone, 2010,46(4):1156-1161.
[9] Qu D, Li J, Li Y, et al. Angiogenesis and osteogenesis enhanced by bFGF ex vivo gene therapy for bone tissue engineering in reconstruction of calvarial defects[J]. J Biomed Mater Res A, 2011, 96(3):543-551.
[10] Bai Y, Li P, Yin G, et al. BMP-2, VEGF and bFGF synergistically promote the osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells[J]. Biotechnol Lett, 2013, 35(3):301-308.
[11] Schonmeyr B H, Soares M, Avraham T, et al. Vascular endothelial growth factor inhibits bone morphogenetic protein 2 expression in rat mesenchymal stem cells[J]. Tissue Eng Part A, 2010,16(2):653-662.
[12] Li G, Corsi-Payne K, Zheng B, et al. The dose of growth factors influences the synergistic effect of vascular endothelial growth factor on bone morphogenetic protein 4-induced ectopic bone formation[J]. Tissue Eng Part A, 2009,15(8):2123-2133.
[13] Liu B, Li X, Liang G, et al. VEGF expression in mesenchymal stem cells promotes bone formation of tissue-engineered bones[J]. Mol Med Report, 2011,4(6):1121-1126.
[14] Lai QG, Yuan KF, Xu X, et al. Transcription factor osterix modified bone marrow mesenchymal stem cells enhance callus formation during distraction osteogenesis[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2011,111(4):412-419.
[15] Xue J, Peng J, Yuan M, et al. NELL1 promotes high-quality bone regeneration in rat femoral distraction osteogenesis model[J]. Bone, 2011,48(3):485-495.
[16] Liu Y, Chen C, He H, et al. Lentiviral-mediated gene transfer into human adipose-derived stem cells: role of NELL1 versus BMP2 in osteogenesis and adipogenesis in vitro[J]. Acta Biochim Biophys Sin (Shanghai), 2012,44(10):856-865.
[17] Guo-Ping W, Xiao-Chuan H, Zhi-Hui Y, et al. Influence on the osteogenic activity of the human bone marrow mesenchymal stem cells transfected by liposome-mediated recombinant plasmid pIRES-hBMP2-hVEGF165 in vitro[J]. Ann Plast Surg, 2010,65(1):80-84.
[18] Xiao C, Zhou H, Liu G, et al. Bone marrow stromal cells with a combined expression of BMP-2 and VEGF-165 enhanced bone regeneration[J]. Biomed Mater, 2011,6(1):15013.
[19] Zhang WB, Zheng LW, Chua DT, et al. Treatment of irradiated mandibles with mesenchymal stem cells transfected with bone morphogenetic protein 2/7[J]. J Oral Maxillofac Surg, 2012,70(7):1711-1716.
[20] Shi Z B, Wang K Z. Effects of recombinant adeno-associated viral vectors on angiopoiesis and osteogenesis in cultured rabbit bone marrow stem cells via co-expressing hVEGF and hBMP genes: a preliminary study in vitro[J]. Tissue Cell, 2010,42(5):314-321.
[21] Qing W, Guang-Xing C, Lin G, et al. The osteogenic study of tissue engineering bone with BMP2 and BMP7 gene-modified rat adipose-derived stem cell[J]. J Biomed Biotechnol, 2012, 2012:410879.
[22] Zhang X, Zhang C, Tang T, et al. Immunomodulatory and osteogenic differentiation effects of mesenchymal stem cells by adenovirus-mediated coexpression of CTLA4Ig and BMP2[J]. J Orthop Res, 2008,26(3):314-321.
[23] Musgrave DS, Bosch P, Lee JY, et al. Ex vivo gene therapy to produce bone using different cell types[J]. Clin Orthop Relat Res, 2000, (378): 290-305.
[24] Vishnubalaji R, Al-Nbaheen M, Kadalmani B, et al. Comparative investigation of the differentiation capability of bone-marrow- and adipose-derived mesenchymal stem cells by qualitative and quantitative analysis[J]. Cell Tissue Res, 2012,347(2):419-427.
[25] Lin L, Shen Q, Wei X, et al. Comparison of osteogenic potentials of BMP4 transduced stem cells from autologous bone marrow and fat tissue in a rabbit model of calvarial defects[J]. Calcif Tissue Int, 2009,85(1):55-65.
[26] Sun JJ, Zheng XH, Wang LY, et al. New bone formation enhanced by ADSCs overexpressing hRunx2 during mandibular distraction osteogenesis in osteoporotic rabbits[J]. J Orthop Res, 2014,32(5):709-720.
[27] 李汶洋,蒋校文,祝颂松,等. bFGF-in vivo基因治疗促进兔下颌牵张成骨的实验研究[J]. 口腔医学研究, 2011,27(7):552-554.
[28] Wu G, Hu C, He X, et al. Effect of gene transfecting at different times on mandibular distraction osteogenesis[J]. J Craniofac Surg, 2013,24(1):232-236.
[29] Park SJ, Na K. The transfection efficiency of photosensitizer-induced gene delivery to human MSCs and internalization rates of EGFP and Runx2 genes[J]. Biomaterials, 2012,33(27):6485-6494.
[30] Kealy B, Liew A, Mcmahon JM, et al. Comparison of viral and nonviral vectors for gene transfer to human endothelial progenitor cells[J]. Tissue Eng Part C Methods, 2009,15(2):223-231.
[31] Choi KS, Ahn SY, Kim TS, et al. Characterization and biodistribution of human mesenchymal stem cells transduced with lentiviral-mediated BMP2[J]. Arch Pharm Res, 2011,34(4):599-606.
[32] Montini E, Cesana D, Schmidt M, et al. Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration[J]. Nat Biotechnol, 2006,24(6):687-696.
[33] 黄旋平. hBMP-2基因修饰自体BMSCs移植促进兔下颌骨牵张成骨新骨形成的实验研究[D]. 广西医科大学, 2011.
[34] Lu K, Zeng D, Zhang Y, et al. BMP-2 gene modified canine bMSCs promote ectopic bone formation mediated by a nonviral PEI derivative[J]. Ann Biomed Eng, 2011,39(6):1829-1839.
[35] Clements BA, Hsu CY, Kucharski C, et al. Nonviral delivery of basic fibroblast growth factor gene to bone marrow stromal cells[J]. Clin Orthop Relat Res, 2009,467(12):3129-3137. |