放射性唾液腺损伤机制的研究进展

doi:10.3969/j.issn.1005-4979.2015.02.015

摘要/Abstract

摘要： 放疗作为头颈部恶性肿瘤主要治疗方法之一，取得了很好的治疗效果。但是头颈部恶性肿瘤放疗之后，不可避免的引起其他组织的辐射损伤，导致各种放疗术后并发症的发生，其中最严重的是放射性唾液腺损伤导致的口干症。关于放射性唾液腺损伤的发生机制，国内外学者已进行了大量研究，但是对于其确切机制尚不清楚，本文就近30年来相关学者对放射性唾液腺损伤的发生机制的研究作一综述。

关键词: 辐射； , 唾液腺损伤； , 口干

Abstract: Radiotherapy is one of the most effective treatments for head and neck Malignancies. However, it often cause some complications.One of the most significant long-term complication of radiotherapy in the head-and-neck region is salivary gland hypofunction or xerostomia. The exact mechanism of radiation-induced salivary gland hypofunction is still not precisely known, though much research has been done. The paper summaries the research progressesonmechanisms of radiation-induced salivary glands damage.

Key words: radiation, salivary gland damage, xerostomia

中图分类号:

R781.7

朱红华，公柏娟，马珊珊，李志民，孙宏晨. 放射性唾液腺损伤机制的研究进展[J]. 《口腔颌面外科杂志》, 2015, 25(2): 148-.

ZHU Hong-hua, GONG Bai-juan, MAShan-shan, LI Zhi-min, SUN Hong-chen. Recent Advances of Radiation-induced Salivary Glands Damage[J]. 《Journal of Oral and Maxillofacial Surgery》, 2015, 25(2): 148-.

https://journal06.magtech.org.cn/Jweb_joms/CN/Y2015/V25/I2/148

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