长链非编码RNA的新认识及与头颈部肿瘤发生的关系

doi:10.3969/j.issn.1005-4979.2015.01.017

摘要/Abstract

摘要： 本文简述了长链非编码RNA（lncRNA）的概念及其功能，以及目前的研究现状，介绍了当前研究较为透彻的几个lncRNA的功能以及其在肿瘤组织中的表达情况，如H19、MALAT1、MEG3、HOTAIR等。着重分析了在头颈部肿瘤研究领域，lncRNA目前的研究进展，提出lncRNA与肿瘤的发生发展关系密切，存在着广阔的研究空间。

关键词: 长链非编码RNA（lncRNA）； , 肿瘤； , 头颈部肿瘤

Abstract: This paper briefly describes the concept and functions of lncRNA and the current situation of research, introduces several functions of lncRNA thoroughly researched at present and their expression in tumor tissues, such as H19, MALAT1, MEG3, HOTAIR, etc. This paper also mainly analyzes the current research progress of lncRNA in the field of head and neck tumors, and proposes that lncRNA is closely related to the occurrence and development of tumors and implies a broad research space.

Key words: long non-coding RNA, tumor, head and neck tumor

中图分类号:

R739.8

韩煦，徐晓刚. 长链非编码RNA的新认识及与头颈部肿瘤发生的关系[J]. 《口腔颌面外科杂志》, 2015, 25(1): 77-.

HAN Xu, XU Xiao-gang. Update on lncRNA and Its Relationship with Head and Neck Tumor[J]. 《Journal of Oral and Maxillofacial Surgery》, 2015, 25(1): 77-.

https://journal06.magtech.org.cn/Jweb_joms/CN/Y2015/V25/I1/77

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