《口腔颌面外科杂志》 ›› 2016, Vol. 26 ›› Issue (2): 135-139. doi: 10.3969/j.issn.1005-4979.2016.02.013

• 综述 • 上一篇    下一篇

多因子释放系统在组织工程领域的应用

刘宁,王佐林   

  1. 同济大学口腔医学院·同济大学附属口腔医院种植科,上海牙组织修复与再生工程技术研究中心,上海  200072
  • 收稿日期:2015-05-26 修回日期:2015-12-20 出版日期:2016-04-28 发布日期:2016-06-07
  • 通讯作者: 王佐林,教授. E-mail:zuolin@tongji.edu.cn
  • 作者简介:刘宁(1986—),女,辽宁人,博士研究生.
  • 基金资助:

    国家科技支撑计划项目(2014BAI04B07);国家自然科学基金面上项目(81271110)

Modern Trends in Multiple Growth Factors Delivery System for Tissue Engineering

LIU Ning, WANG Zuo-lin   

  1. Department of Oral Implant, School and Hospital of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072,China
  • Received:2015-05-26 Revised:2015-12-20 Online:2016-04-28 Published:2016-06-07

摘要: 生长因子是细胞合成和分泌的一类活性蛋白质,在促进组织再生、修复及创伤愈合等方面发挥重要作用。生理性的组织修复与再生过程是在多种生长因子共同调节下完成的,因此模拟生理性组织修复过程,可控性释放多种生长因子在组织工程领域具有广阔的应用前景。

关键词:  , 生长因子,  ,  , 载体,  ,  , 释放模式,  ,  , 组织工程

Abstract: Growth factors are a group of activated proteins synthesized and excreted from cells, which play a critical role in wound healing, tissue repair and tissue regeneration. Natural tissue repair and regeneration processes are regulated by multiple growth factors, thus mimic the natural healing processes, controlled release multiple growth factors is a promising application in tissue engineering.

Key words: growth factor, carrier, release pattern, tissue engineering

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